Planning, implementation, and sustaining high coverage of human papillomavirus (HPV) vaccination programs: What works in the context of low-resource countries?
Cervical cancer due to human papillomavirus (HPV) infection is a leading cause of mortality among women in low-resource settings. Many Sub-Saharan African countries have introduced HPV vaccination programs at the national level in the last few years. However, countries are struggling to maintain sus...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-04-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2023.1112981/full |
| _version_ | 1797847239740096512 |
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| author | Dur-E-Nayab Waheed Ana Bolio Dominique Guillaume Dominique Guillaume Dominique Guillaume Anissa Sidibe Christopher Morgan Christopher Morgan Emilie Karafillakis Emilie Karafillakis Megan Holloway Pierre Van Damme Rupali Limaye Rupali Limaye Rupali Limaye Rupali Limaye Alex Vorsters |
| author_facet | Dur-E-Nayab Waheed Ana Bolio Dominique Guillaume Dominique Guillaume Dominique Guillaume Anissa Sidibe Christopher Morgan Christopher Morgan Emilie Karafillakis Emilie Karafillakis Megan Holloway Pierre Van Damme Rupali Limaye Rupali Limaye Rupali Limaye Rupali Limaye Alex Vorsters |
| author_sort | Dur-E-Nayab Waheed |
| collection | DOAJ |
| description | Cervical cancer due to human papillomavirus (HPV) infection is a leading cause of mortality among women in low-resource settings. Many Sub-Saharan African countries have introduced HPV vaccination programs at the national level in the last few years. However, countries are struggling to maintain sustainable coverage. This study focuses on the introduction and sustainability challenges, context-specific key lessons learned, and mechanisms of action to achieve high sustainable coverage from low and lower-middle-income countries (LLMICs) that have introduced HPV vaccination programs by collating evidence from a literature review and key informant interviews. Local data availability was a challenge across countries, with the lack or absence of registries, data collection and reporting mechanisms. Multi-sectoral coordination and early involvement of key stakeholders were cited as an integral part of HPV programs and facilitators for sustainable coverage. Key informants identified periodic sensitization and training as critical due to high staff turnover. Health workforce mobilization was fundamental to ensure that the health workforce is aware of the disease etiology, eligibility requirements, and can dispel misinformation. Schools were reported to be an ideal sustainable platform for vaccination. However, this required teachers to be trained, which was often not considered in the programs. District-level staff were often poorly informed and lacked the technical and logistic capacity to support vaccination rounds and data collection. To improve the sustainability of HPV vaccination programs, there is a need for timely microplanning, efficient preparedness assessment, assessing training approaches, periodic training, finding innovative ways to achieve equity and adoption of a bottom-up approach to ensure that processes between districts and central level are well-connected and resources are distributed efficiently. |
| first_indexed | 2024-04-09T18:08:06Z |
| format | Article |
| id | doaj.art-a1fc54fb7fe44f449e48170b2578cfa3 |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-04-09T18:08:06Z |
| publishDate | 2023-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-a1fc54fb7fe44f449e48170b2578cfa32023-04-14T05:05:19ZengFrontiers Media S.A.Frontiers in Public Health2296-25652023-04-011110.3389/fpubh.2023.11129811112981Planning, implementation, and sustaining high coverage of human papillomavirus (HPV) vaccination programs: What works in the context of low-resource countries?Dur-E-Nayab Waheed0Ana Bolio1Dominique Guillaume2Dominique Guillaume3Dominique Guillaume4Anissa Sidibe5Christopher Morgan6Christopher Morgan7Emilie Karafillakis8Emilie Karafillakis9Megan Holloway10Pierre Van Damme11Rupali Limaye12Rupali Limaye13Rupali Limaye14Rupali Limaye15Alex Vorsters16Centre for the Evaluation of Vaccination, University of Antwerp, Antwerp, BelgiumDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United KingdomJhpiego, The Johns Hopkins University Affiliate, Baltimore, MD, United StatesInternational Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United StatesCenter for Infectious Disease and Nursing Innovation, School of Nursing, Johns Hopkins University, Baltimore, MD, United StatesDepartment of Vaccine Programmes, Gavi, the Vaccine Alliance, Geneva, SwitzerlandJhpiego, The Johns Hopkins University Affiliate, Baltimore, MD, United StatesNossal Institute for Global Health, School of Population and Global Health, University of Melbourne, Melbourne, VIC, AustraliaCentre for the Evaluation of Vaccination, University of Antwerp, Antwerp, BelgiumDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United KingdomDepartment of Vaccine Programmes, Gavi, the Vaccine Alliance, Geneva, SwitzerlandCentre for the Evaluation of Vaccination, University of Antwerp, Antwerp, BelgiumInternational Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United StatesDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United StatesDepartment of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States0Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United StatesCentre for the Evaluation of Vaccination, University of Antwerp, Antwerp, BelgiumCervical cancer due to human papillomavirus (HPV) infection is a leading cause of mortality among women in low-resource settings. Many Sub-Saharan African countries have introduced HPV vaccination programs at the national level in the last few years. However, countries are struggling to maintain sustainable coverage. This study focuses on the introduction and sustainability challenges, context-specific key lessons learned, and mechanisms of action to achieve high sustainable coverage from low and lower-middle-income countries (LLMICs) that have introduced HPV vaccination programs by collating evidence from a literature review and key informant interviews. Local data availability was a challenge across countries, with the lack or absence of registries, data collection and reporting mechanisms. Multi-sectoral coordination and early involvement of key stakeholders were cited as an integral part of HPV programs and facilitators for sustainable coverage. Key informants identified periodic sensitization and training as critical due to high staff turnover. Health workforce mobilization was fundamental to ensure that the health workforce is aware of the disease etiology, eligibility requirements, and can dispel misinformation. Schools were reported to be an ideal sustainable platform for vaccination. However, this required teachers to be trained, which was often not considered in the programs. District-level staff were often poorly informed and lacked the technical and logistic capacity to support vaccination rounds and data collection. To improve the sustainability of HPV vaccination programs, there is a need for timely microplanning, efficient preparedness assessment, assessing training approaches, periodic training, finding innovative ways to achieve equity and adoption of a bottom-up approach to ensure that processes between districts and central level are well-connected and resources are distributed efficiently.https://www.frontiersin.org/articles/10.3389/fpubh.2023.1112981/fullHPV vaccinationlow-and lower-middle-income countrieshuman papillomavirusvaccine implementationbarriers and facilitating factors |
| spellingShingle | Dur-E-Nayab Waheed Ana Bolio Dominique Guillaume Dominique Guillaume Dominique Guillaume Anissa Sidibe Christopher Morgan Christopher Morgan Emilie Karafillakis Emilie Karafillakis Megan Holloway Pierre Van Damme Rupali Limaye Rupali Limaye Rupali Limaye Rupali Limaye Alex Vorsters Planning, implementation, and sustaining high coverage of human papillomavirus (HPV) vaccination programs: What works in the context of low-resource countries? Frontiers in Public Health HPV vaccination low-and lower-middle-income countries human papillomavirus vaccine implementation barriers and facilitating factors |
| title | Planning, implementation, and sustaining high coverage of human papillomavirus (HPV) vaccination programs: What works in the context of low-resource countries? |
| title_full | Planning, implementation, and sustaining high coverage of human papillomavirus (HPV) vaccination programs: What works in the context of low-resource countries? |
| title_fullStr | Planning, implementation, and sustaining high coverage of human papillomavirus (HPV) vaccination programs: What works in the context of low-resource countries? |
| title_full_unstemmed | Planning, implementation, and sustaining high coverage of human papillomavirus (HPV) vaccination programs: What works in the context of low-resource countries? |
| title_short | Planning, implementation, and sustaining high coverage of human papillomavirus (HPV) vaccination programs: What works in the context of low-resource countries? |
| title_sort | planning implementation and sustaining high coverage of human papillomavirus hpv vaccination programs what works in the context of low resource countries |
| topic | HPV vaccination low-and lower-middle-income countries human papillomavirus vaccine implementation barriers and facilitating factors |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2023.1112981/full |
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