Neutralizing Antibody Induction Associated with a Germline Immunoglobulin Gene Polymorphism in Neutralization-Resistant SIVsmE543-3 Infection

Neutralizing Antibody Induction Associated with a Germline Immunoglobulin Gene Polymorphism in Neutralization-Resistant SIVsmE543-3 Infection

Antibody responses are crucial for the control of virus infection. Understanding of the mechanism of antibody induction is important for the development of a vaccine eliciting effective anti-virus antibodies. Virus-specific B cell receptor (BCR)/antibody repertoires are different among individuals,...

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Bibliographic Details
Main Authors: Yuto Nomura, Saori Matsuoka, Midori Okazaki, Takeo Kuwata, Tetsuro Matano, Hiroshi Ishii
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Viruses
Subjects:
SIV
neutralizing antibody
B cell receptor
germline
polymorphism
Online Access:https://www.mdpi.com/1999-4915/13/6/1181

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