Applications of Laser Speckle Contrast Imaging Technology in Dermatology
Laser speckle contrast imaging or laser speckle imaging (LSI) is a noninvasive imaging technology that can detect areas of dynamic perfusion or vascular flow. Thus, LSI has shown increasing diagnostic utility in various pathologies and has been employed for intraoperative, postoperative, and long-te...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-09-01
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| Series: | JID Innovations |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667026723000085 |
| _version_ | 1797674154152951808 |
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| author | Courtney Linkous Angel D. Pagan Chelsea Shope Laura Andrews Alan Snyder Tong Ye Manuel Valdebran |
| author_facet | Courtney Linkous Angel D. Pagan Chelsea Shope Laura Andrews Alan Snyder Tong Ye Manuel Valdebran |
| author_sort | Courtney Linkous |
| collection | DOAJ |
| description | Laser speckle contrast imaging or laser speckle imaging (LSI) is a noninvasive imaging technology that can detect areas of dynamic perfusion or vascular flow. Thus, LSI has shown increasing diagnostic utility in various pathologies and has been employed for intraoperative, postoperative, and long-term monitoring in many medical specialties. Recently, LSI has gained traction in clinical dermatology because it can be effective in the assessment of pathologies that are associated with increased perfusion and hypervascularity compared with that of normal tissue. To date, LSI has been found to be highly accurate in monitoring skin graft reperfusion, determining the severity of burns, evaluating neurosurgical revascularization, assessing persistent perfusion in capillary malformations after laser therapy, and differentiating malignant and benign skin lesions. LSI affords the advantage of noninvasively assessing lesions before more invasive methods of diagnosis, such as tissue biopsy, while remaining inexpensive and exhibiting no adverse events to date. However, potential obstacles to its clinical use include tissue movement artifact, primarily qualitative data, and unclear impact on clinical practice given the lack of superiority data compared with the current standard-of-care diagnostic methods. In this review, we discuss the clinical applications of LSI in dermatology for use in the diagnosis and monitoring of vascular, neoplastic, and inflammatory skin conditions. |
| first_indexed | 2024-03-11T21:54:55Z |
| format | Article |
| id | doaj.art-a1ff4c02040a4d5bad861bb061052f8b |
| institution | Directory Open Access Journal |
| issn | 2667-0267 |
| language | English |
| last_indexed | 2024-03-11T21:54:55Z |
| publishDate | 2023-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JID Innovations |
| spelling | doaj.art-a1ff4c02040a4d5bad861bb061052f8b2023-09-26T04:12:41ZengElsevierJID Innovations2667-02672023-09-0135100187Applications of Laser Speckle Contrast Imaging Technology in DermatologyCourtney Linkous0Angel D. Pagan1Chelsea Shope2Laura Andrews3Alan Snyder4Tong Ye5Manuel Valdebran6College of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA; Correspondence: Courtney Linkous, Department of Dermatology, College of Medicine, Medical University of South Carolina, 135 Rutledge Avenue, 11th floor, Charleston, South Carolina 29425, USA.School of Medicine, Ponce Health Sciences University, Ponce, Puerto Rico, USACollege of Medicine, Medical University of South Carolina, Charleston, South Carolina, USACollege of Medicine, Medical University of South Carolina, Charleston, South Carolina, USADepartment of Dermatology & Dermatologic Surgery, College of Medicine, Medical University of South Carolina, Charleston, South Carolina, USADepartment of Bioengineering, Clemson University, Clemson, South Carolina, USA; Department of Regenerative Medicine & Cell Biology, College of Medicine, Medical University of South Carolina, Charleston, South Carolina, USADepartment of Dermatology & Dermatologic Surgery, College of Medicine, Medical University of South Carolina, Charleston, South Carolina, USALaser speckle contrast imaging or laser speckle imaging (LSI) is a noninvasive imaging technology that can detect areas of dynamic perfusion or vascular flow. Thus, LSI has shown increasing diagnostic utility in various pathologies and has been employed for intraoperative, postoperative, and long-term monitoring in many medical specialties. Recently, LSI has gained traction in clinical dermatology because it can be effective in the assessment of pathologies that are associated with increased perfusion and hypervascularity compared with that of normal tissue. To date, LSI has been found to be highly accurate in monitoring skin graft reperfusion, determining the severity of burns, evaluating neurosurgical revascularization, assessing persistent perfusion in capillary malformations after laser therapy, and differentiating malignant and benign skin lesions. LSI affords the advantage of noninvasively assessing lesions before more invasive methods of diagnosis, such as tissue biopsy, while remaining inexpensive and exhibiting no adverse events to date. However, potential obstacles to its clinical use include tissue movement artifact, primarily qualitative data, and unclear impact on clinical practice given the lack of superiority data compared with the current standard-of-care diagnostic methods. In this review, we discuss the clinical applications of LSI in dermatology for use in the diagnosis and monitoring of vascular, neoplastic, and inflammatory skin conditions.http://www.sciencedirect.com/science/article/pii/S2667026723000085 |
| spellingShingle | Courtney Linkous Angel D. Pagan Chelsea Shope Laura Andrews Alan Snyder Tong Ye Manuel Valdebran Applications of Laser Speckle Contrast Imaging Technology in Dermatology JID Innovations |
| title | Applications of Laser Speckle Contrast Imaging Technology in Dermatology |
| title_full | Applications of Laser Speckle Contrast Imaging Technology in Dermatology |
| title_fullStr | Applications of Laser Speckle Contrast Imaging Technology in Dermatology |
| title_full_unstemmed | Applications of Laser Speckle Contrast Imaging Technology in Dermatology |
| title_short | Applications of Laser Speckle Contrast Imaging Technology in Dermatology |
| title_sort | applications of laser speckle contrast imaging technology in dermatology |
| url | http://www.sciencedirect.com/science/article/pii/S2667026723000085 |
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