Multicentric Castleman's disease: Report of three cases
Castleman's disease is an uncommon benign B-cell lymphoproliferative disorder. According to lymph nodes distribution, there are two distinct subtypes of disease: unicentric and multicentric. Unicentric Castleman's disease is more common, localized to one site, and locally treated. On the c...
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Elsevier
2019-03-01
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Series: | Radiology Case Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043317304879 |
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author | M. Guazzaroni, MD PhD F. Bocchinfuso, MD E. Vasili, MD A. Lacchè, MD T. Ranalli, MD A. Garipoli, MD F. Di Tosto, MD R. Floris, MD PhD |
author_facet | M. Guazzaroni, MD PhD F. Bocchinfuso, MD E. Vasili, MD A. Lacchè, MD T. Ranalli, MD A. Garipoli, MD F. Di Tosto, MD R. Floris, MD PhD |
author_sort | M. Guazzaroni, MD PhD |
collection | DOAJ |
description | Castleman's disease is an uncommon benign B-cell lymphoproliferative disorder. According to lymph nodes distribution, there are two distinct subtypes of disease: unicentric and multicentric. Unicentric Castleman's disease is more common, localized to one site, and locally treated. On the contrary, multicentric form is a rare systemic disease characterized by diffuse lymphadenopathy and inflammatory symptoms. We report three cases of persons that were initially suspected to have a lymphoma but were later histologically confirmed to have Multicentric Castleman's Disease. In addition, our work aims to investigate the role of fluorodeoxyglucose (FDG) PET/CT in evaluation of this rare condition. Keywords: Multicentric Castleman's disease, Hyaline vascular type, FDG PET/CT |
first_indexed | 2024-12-11T23:11:13Z |
format | Article |
id | doaj.art-a2021371d41b4e77ab655901994278df |
institution | Directory Open Access Journal |
issn | 1930-0433 |
language | English |
last_indexed | 2024-12-11T23:11:13Z |
publishDate | 2019-03-01 |
publisher | Elsevier |
record_format | Article |
series | Radiology Case Reports |
spelling | doaj.art-a2021371d41b4e77ab655901994278df2022-12-22T00:46:42ZengElsevierRadiology Case Reports1930-04332019-03-01143328332Multicentric Castleman's disease: Report of three casesM. Guazzaroni, MD PhD0F. Bocchinfuso, MD1E. Vasili, MD2A. Lacchè, MD3T. Ranalli, MD4A. Garipoli, MD5F. Di Tosto, MD6R. Floris, MD PhD7Department of Diagnostic and Molecular Imaging, Interventional Radiology and Radiation Therapy, Fondazione Policlinico “Tor Vergata,” viale Oxford 81, Rome 00133, ItalyDepartment of Diagnostic and Molecular Imaging, Interventional Radiology and Radiation Therapy, Fondazione Policlinico “Tor Vergata,” viale Oxford 81, Rome 00133, ItalyDepartment of Diagnostic and Molecular Imaging, Interventional Radiology and Radiation Therapy, Fondazione Policlinico “Tor Vergata,” viale Oxford 81, Rome 00133, ItalyDepartment of Diagnostic and Molecular Imaging, Interventional Radiology and Radiation Therapy, Fondazione Policlinico “Tor Vergata,” viale Oxford 81, Rome 00133, ItalyDepartment of Diagnostic and Molecular Imaging, Interventional Radiology and Radiation Therapy, Fondazione Policlinico “Tor Vergata,” viale Oxford 81, Rome 00133, ItalyDepartment of Diagnostic and Molecular Imaging, Interventional Radiology and Radiation Therapy, Fondazione Policlinico “Tor Vergata,” viale Oxford 81, Rome 00133, ItalyDepartment of Diagnostic and Molecular Imaging, Interventional Radiology and Radiation Therapy, Fondazione Policlinico “Tor Vergata,” viale Oxford 81, Rome 00133, ItalyDepartment of Diagnostic and Molecular Imaging, Interventional Radiology and Radiation Therapy, Fondazione Policlinico “Tor Vergata,” viale Oxford 81, Rome 00133, ItalyCastleman's disease is an uncommon benign B-cell lymphoproliferative disorder. According to lymph nodes distribution, there are two distinct subtypes of disease: unicentric and multicentric. Unicentric Castleman's disease is more common, localized to one site, and locally treated. On the contrary, multicentric form is a rare systemic disease characterized by diffuse lymphadenopathy and inflammatory symptoms. We report three cases of persons that were initially suspected to have a lymphoma but were later histologically confirmed to have Multicentric Castleman's Disease. In addition, our work aims to investigate the role of fluorodeoxyglucose (FDG) PET/CT in evaluation of this rare condition. Keywords: Multicentric Castleman's disease, Hyaline vascular type, FDG PET/CThttp://www.sciencedirect.com/science/article/pii/S1930043317304879 |
spellingShingle | M. Guazzaroni, MD PhD F. Bocchinfuso, MD E. Vasili, MD A. Lacchè, MD T. Ranalli, MD A. Garipoli, MD F. Di Tosto, MD R. Floris, MD PhD Multicentric Castleman's disease: Report of three cases Radiology Case Reports |
title | Multicentric Castleman's disease: Report of three cases |
title_full | Multicentric Castleman's disease: Report of three cases |
title_fullStr | Multicentric Castleman's disease: Report of three cases |
title_full_unstemmed | Multicentric Castleman's disease: Report of three cases |
title_short | Multicentric Castleman's disease: Report of three cases |
title_sort | multicentric castleman s disease report of three cases |
url | http://www.sciencedirect.com/science/article/pii/S1930043317304879 |
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