Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing

Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing

Abstract Background Stool is an important diagnostic specimen for tuberculosis in populations who struggle to provide sputum, such as children or people living with HIV. However, the culture of Mycobacterium tuberculosis (M. tuberculosis) complex strains from stool perform poorly. This limits the op...

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Bibliographic Details
Main Authors: Doctor B. Sibandze, Alexander Kay, Viola Dreyer, Welile Sikhondze, Qiniso Dlamini, Andrew DiNardo, Godwin Mtetwa, Bhekumusa Lukhele, Debrah Vambe, Christoph Lange, Muyalo Glenn Dlamini, Tara Ness, Rojelio Mejia, Barbara Kalsdorf, Jan Heyckendorf, Martin Kuhns, Florian P. Maurer, Sindisiwe Dlamini, Gugu Maphalala, Stefan Niemann, Anna Mandalakas
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Genome Medicine
Subjects:
Tuberculosis
Drug resistance
Feces
Online Access:https://doi.org/10.1186/s13073-022-01054-6

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