Factors Associated with Variability in Pulse Wave Transit Time Using Pulse Oximetry: A Retrospective Study
Pulse wave transit time (PWTT) is the time difference between the occurrence of an R-wave on an electrocardiogram and the detection of pulsatile signals on a pulse oximeter, which reflects changes in blood pressure (BP) corresponding to the vessel wall compliance. However, the factors affecting PWTT...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/14/3963 |
| _version_ | 1797446300720955392 |
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| author | Hilmanda Budiman Ryo Wakita Takaya Ito Shigeru Maeda |
| author_facet | Hilmanda Budiman Ryo Wakita Takaya Ito Shigeru Maeda |
| author_sort | Hilmanda Budiman |
| collection | DOAJ |
| description | Pulse wave transit time (PWTT) is the time difference between the occurrence of an R-wave on an electrocardiogram and the detection of pulsatile signals on a pulse oximeter, which reflects changes in blood pressure (BP) corresponding to the vessel wall compliance. However, the factors affecting PWTT variability have not been determined. Thus, we investigated the BP changes associated with variations in PWTT and identified the clinical characteristics associated with these variations. Data related to 605 cases of dental procedures performed under intravenous conscious sedation from April 2020 to November 2021 were collected, and 485 cases were enrolled. Heart rate, systolic blood pressure before and after local anesthesia (LA) administration, and crest and trough PWTT waves during LA administration were recorded. Thereafter, PWTT variability was calculated; cases were divided into two groups: large PWTT variability (LPV, <i>n</i> = 357) and small PWTT variability (SPV, <i>n</i> = 128). The index of large PWTT variability could not detect changes in BP. Logistic regression analysis revealed that factors, such as LA use, age, hypertension, and dental treatment phobia were associated with PWTT variability. The use of epinephrine more than 36.25 µg in each LA resulted in PWTT variability of more than 15 ms. |
| first_indexed | 2024-03-09T13:38:20Z |
| format | Article |
| id | doaj.art-a209618158c6495c9275c961b145b5b8 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T13:38:20Z |
| publishDate | 2022-07-01 |
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| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-a209618158c6495c9275c961b145b5b82023-11-30T21:09:44ZengMDPI AGJournal of Clinical Medicine2077-03832022-07-011114396310.3390/jcm11143963Factors Associated with Variability in Pulse Wave Transit Time Using Pulse Oximetry: A Retrospective StudyHilmanda Budiman0Ryo Wakita1Takaya Ito2Shigeru Maeda3Department of Dental Anesthesiology and Orofacial Pain Management, Tokyo Medical and Dental University, Yushima, Bunkyo-ku 1-5-45, Tokyo 113-8549, JapanDepartment of Dental Anesthesiology and Orofacial Pain Management, Tokyo Medical and Dental University, Yushima, Bunkyo-ku 1-5-45, Tokyo 113-8549, JapanDepartment of Dental Anesthesiology and Orofacial Pain Management, Tokyo Medical and Dental University, Yushima, Bunkyo-ku 1-5-45, Tokyo 113-8549, JapanDepartment of Dental Anesthesiology and Orofacial Pain Management, Tokyo Medical and Dental University, Yushima, Bunkyo-ku 1-5-45, Tokyo 113-8549, JapanPulse wave transit time (PWTT) is the time difference between the occurrence of an R-wave on an electrocardiogram and the detection of pulsatile signals on a pulse oximeter, which reflects changes in blood pressure (BP) corresponding to the vessel wall compliance. However, the factors affecting PWTT variability have not been determined. Thus, we investigated the BP changes associated with variations in PWTT and identified the clinical characteristics associated with these variations. Data related to 605 cases of dental procedures performed under intravenous conscious sedation from April 2020 to November 2021 were collected, and 485 cases were enrolled. Heart rate, systolic blood pressure before and after local anesthesia (LA) administration, and crest and trough PWTT waves during LA administration were recorded. Thereafter, PWTT variability was calculated; cases were divided into two groups: large PWTT variability (LPV, <i>n</i> = 357) and small PWTT variability (SPV, <i>n</i> = 128). The index of large PWTT variability could not detect changes in BP. Logistic regression analysis revealed that factors, such as LA use, age, hypertension, and dental treatment phobia were associated with PWTT variability. The use of epinephrine more than 36.25 µg in each LA resulted in PWTT variability of more than 15 ms.https://www.mdpi.com/2077-0383/11/14/3963pulse wave transit timeambulatory monitoringhemodynamic monitoringlocal anesthetics |
| spellingShingle | Hilmanda Budiman Ryo Wakita Takaya Ito Shigeru Maeda Factors Associated with Variability in Pulse Wave Transit Time Using Pulse Oximetry: A Retrospective Study Journal of Clinical Medicine pulse wave transit time ambulatory monitoring hemodynamic monitoring local anesthetics |
| title | Factors Associated with Variability in Pulse Wave Transit Time Using Pulse Oximetry: A Retrospective Study |
| title_full | Factors Associated with Variability in Pulse Wave Transit Time Using Pulse Oximetry: A Retrospective Study |
| title_fullStr | Factors Associated with Variability in Pulse Wave Transit Time Using Pulse Oximetry: A Retrospective Study |
| title_full_unstemmed | Factors Associated with Variability in Pulse Wave Transit Time Using Pulse Oximetry: A Retrospective Study |
| title_short | Factors Associated with Variability in Pulse Wave Transit Time Using Pulse Oximetry: A Retrospective Study |
| title_sort | factors associated with variability in pulse wave transit time using pulse oximetry a retrospective study |
| topic | pulse wave transit time ambulatory monitoring hemodynamic monitoring local anesthetics |
| url | https://www.mdpi.com/2077-0383/11/14/3963 |
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