Development of Epirubicin-Loaded Biocompatible Polymer PLA–PEG–PLA Nanoparticles: Synthesis, Characterization, Stability, and In Vitro Anticancerous Assessment

Development of Epirubicin-Loaded Biocompatible Polymer PLA–PEG–PLA Nanoparticles: Synthesis, Characterization, Stability, and In Vitro Anticancerous Assessment

Epirubicin (EPI) is an anti-cancerous chemotherapeutic drug that is an effective epimer of doxorubicin with less cardiotoxicity. Although EPI has fewer side effects than its analog, doxorubicin, this study aims to develop EPI nanoparticles as an improved formula of the conventional treatment of EPI...

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Bibliographic Details
Main Authors: Salam Massadeh, Iman Almohammed, Eman Barhoush, Mustafa Omer, Nouf Aldhawi, Abdulaziz Almalik, Manal Alaamery
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Polymers
Subjects:
epirubicin
biocompatible
polymers
nanoparticles
stability studies
sustained release
Online Access:https://www.mdpi.com/2073-4360/13/8/1212

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