A synthetic method to assay polycystin channel biophysics

A synthetic method to assay polycystin channel biophysics

Ion channels are biological transistors that control ionic flux across cell membranes to regulate electrical transmission and signal transduction. They are found in all biological membranes and their conductive state kinetics are frequently disrupted in human diseases. Organelle ion channels are amo...

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Bibliographic Details
Main Authors: Megan Larmore, Orhi Esarte Palomero, Neha Kamat, Paul G DeCaen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-10-01
Series:eLife
Subjects:
ion channels
synthetic biology
polycystins
ADPKD
PKD
biophysics
Online Access:https://elifesciences.org/articles/98534

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