Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex
The mammalian circadian clock is driven by a transcriptional–translational feedback loop, which produces robust 24-hr rhythms. Proper oscillation of the clock depends on the complex formation and periodic turnover of the Period and Cryptochrome proteins, which together inhibit their own transcriptio...
Main Authors: | Shannon N Nangle, Clark Rosensweig, Nobuya Koike, Hajime Tei, Joseph S Takahashi, Carla B Green, Ning Zheng |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2014-08-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/03674 |
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