Exploring the Metabolic Vulnerabilities of Epithelial–Mesenchymal Transition in Breast Cancer

Exploring the Metabolic Vulnerabilities of Epithelial–Mesenchymal Transition in Breast Cancer

Metastasis and drug resistance are the leading causes of death for breast cancer patients. Epithelial–mesenchymal transition (EMT), a transition from polarized epithelial cells to motile mesenchymal cells mediated by a series of activation signals, confers breast tumor cells with enhanced stem cell,...

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Bibliographic Details
Main Authors: Xiangyu Sun, Mozhi Wang, Mengshen Wang, Litong Yao, Xinyan Li, Haoran Dong, Meng Li, Xiang Li, Xing Liu, Yingying Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
breast neoplasms
epithelial–mesenchymal transition
metabolic reprogramming
glycolysis
metastasis
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00655/full

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