OxLDL induces the release of IL-1β from primed human endothelial and smooth muscle cells via different caspase -1-dependent mechanisms

OxLDL induces the release of IL-1β from primed human endothelial and smooth muscle cells via different caspase -1-dependent mechanisms

Atherosclerosis is characterised by abnormal lipid and cell accumulation within arterial layers that leads to disturbed blood flow. Modified cholesterol forms such as oxidised low-density lipoprotein (oxLDL) enter cells altering their phenotype, triggering over-exuberant repair and arterial occlusio...

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Bibliographic Details
Main Authors: Majid Almansouri, Pooja Patel, Janet Chamberlain, Sheila Francis
Format: Article
Language:English
Published: Bioscientifica 2022-09-01
Series:Vascular Biology
Subjects:
hcaecs
hcasmcs
atherosclerosis
oxldl
caspase-1
gasdermin d
il-1β
Online Access:https://vb.bioscientifica.com/view/journals/vb/4/1/VB-22-0009.xml

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