Synthesis, Biophysical Interaction of DNA/BSA, Equilibrium and Stopped-Flow Kinetic Studies, and Biological Evaluation of bis(2-Picolyl)amine-Based Nickel(II) Complex

Synthesis, Biophysical Interaction of DNA/BSA, Equilibrium and Stopped-Flow Kinetic Studies, and Biological Evaluation of bis(2-Picolyl)amine-Based Nickel(II) Complex

Reaction of bis(2-picolyl)amine (<b>BPA</b>) with Ni(II) salt yielded [(BPA)NiCl<sub>2</sub>(H<sub>2</sub>O)] (<b>NiBPA</b>). The Ni(II) in <b>NiBPA</b> bound to a <b>BPA</b> ligand, two chloride, and one aqua ligands. Because m...

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Bibliographic Details
Main Authors: Esraa Ramzy, Mohamed M. Ibrahim, Ibrahim M. El-Mehasseb, Abd El-Motaleb M. Ramadan, Fawzia I. Elshami, Shaban Y. Shaban, Rudi van Eldik
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biomimetics
Subjects:
DNA/protein affinity
association/dissociation
metallodrugs
nickel complexes
biological activity
Online Access:https://www.mdpi.com/2313-7673/7/4/172

Internet

https://www.mdpi.com/2313-7673/7/4/172

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