Impact of miRNA sequence on miRNA expression and correlation between miRNA expression and cell cycle regulation in breast cancer cells.

The miRNAs regulate cell functions by inhibiting expression of proteins. Research on miRNAs had usually focused on identifying targets by base pairing between miRNAs and their targets. Instead of identifying targets, this paper proposed an innovative approach, namely impact significance analysis, to...

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Detalles Bibliográficos
Main Authors: Zijun Luo, Yi Zhao, Robert Azencott
Formato: Artigo
Idioma:English
Publicado: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC3991594?pdf=render