Imaging neurovascular, endothelial and structural integrity in preparation to treat small vessel diseases. The INVESTIGATE-SVDs study protocol. Part of the SVDs@Target project

Imaging neurovascular, endothelial and structural integrity in preparation to treat small vessel diseases. The INVESTIGATE-SVDs study protocol. Part of the SVDs@Target project

Background: Sporadic cerebral small vessel disease (SVD) and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) share clinical and neuroimaging features and possibly vascular dysfunction(s). However few studies have included both conditions, assessed...

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Main Authors: Gordon W. Blair, Michael S. Stringer, Michael J. Thrippleton, Francesca M. Chappell, Kirsten Shuler, Iona Hamilton, Daniela Jaime Garcia, Fergus N. Doubal, Anna Kopczak, Marco Duering, Michael Ingrisch, Danielle Kerkhofs, Julie Staals, Hilde van den Brink, Tine Arts, Walter H Backes, Robert van Oostenbrugge, Geert Jan Biessels, Martin Dichgans, Joanna M. Wardlaw
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cerebral Circulation - Cognition and Behavior
Subjects:
Cerebral small vessel disease
CADASIL
Cerebrovascular reactivity
Blood-brain barrier permeability
MRI
Online Access:http://www.sciencedirect.com/science/article/pii/S2666245021000179

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