Fungal Chitin Reduces Platelet Activation Mediated via TLR8 Stimulation

Fungal Chitin Reduces Platelet Activation Mediated via TLR8 Stimulation

Platelets play an important role in the innate immune response. During candidaemia, circulating fungal polysaccharides, including chitin, are released into the bloodstream and can interact with platelets and induce modulation of platelet activities. However, the role of circulating chitin in platele...

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Bibliographic Details
Main Authors: Jordan Leroy, Clovis Bortolus, Karine Lecointe, Melissa Parny, Rogatien Charlet, Boualem Sendid, Samir Jawhara
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Candida albicans
chitin
platelets
neutrophils
Toll-like receptor
P-selectin
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00383/full

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