Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila

How the Drosophila lymph gland hemocytes develop and are regulated at a single-cell level is unclear. Here, the authors use single-cell RNA sequencing to show heterogeneity of developing hemocytes in the lymph gland and how they react to wasp infestation, and compare hemocytes from two independent o...

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Main Authors: Bumsik Cho, Sang-Ho Yoon, Daewon Lee, Ferdinand Koranteng, Sudhir Gopal Tattikota, Nuri Cha, Mingyu Shin, Hobin Do, Yanhui Hu, Sue Young Oh, Daehan Lee, A. Vipin Menon, Seok Jun Moon, Norbert Perrimon, Jin-Wu Nam, Jiwon Shim
Format: Article
Language:English
Published: Nature Portfolio 2020-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18135-y
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author Bumsik Cho
Sang-Ho Yoon
Daewon Lee
Ferdinand Koranteng
Sudhir Gopal Tattikota
Nuri Cha
Mingyu Shin
Hobin Do
Yanhui Hu
Sue Young Oh
Daehan Lee
A. Vipin Menon
Seok Jun Moon
Norbert Perrimon
Jin-Wu Nam
Jiwon Shim
author_facet Bumsik Cho
Sang-Ho Yoon
Daewon Lee
Ferdinand Koranteng
Sudhir Gopal Tattikota
Nuri Cha
Mingyu Shin
Hobin Do
Yanhui Hu
Sue Young Oh
Daehan Lee
A. Vipin Menon
Seok Jun Moon
Norbert Perrimon
Jin-Wu Nam
Jiwon Shim
author_sort Bumsik Cho
collection DOAJ
description How the Drosophila lymph gland hemocytes develop and are regulated at a single-cell level is unclear. Here, the authors use single-cell RNA sequencing to show heterogeneity of developing hemocytes in the lymph gland and how they react to wasp infestation, and compare hemocytes from two independent origins.
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spelling doaj.art-a217d9fbf42943298b9152638532fa932022-12-21T18:02:25ZengNature PortfolioNature Communications2041-17232020-09-0111111810.1038/s41467-020-18135-ySingle-cell transcriptome maps of myeloid blood cell lineages in DrosophilaBumsik Cho0Sang-Ho Yoon1Daewon Lee2Ferdinand Koranteng3Sudhir Gopal Tattikota4Nuri Cha5Mingyu Shin6Hobin Do7Yanhui Hu8Sue Young Oh9Daehan Lee10A. Vipin Menon11Seok Jun Moon12Norbert Perrimon13Jin-Wu Nam14Jiwon Shim15Department of Life Sciences, College of Natural Science, Hanyang UniversityDepartment of Life Sciences, College of Natural Science, Hanyang UniversityDepartment of Life Sciences, College of Natural Science, Hanyang UniversityDepartment of Life Sciences, College of Natural Science, Hanyang UniversityDepartment of Genetics, Harvard Medical SchoolDepartment of Life Sciences, College of Natural Science, Hanyang UniversityDepartment of Life Sciences, College of Natural Science, Hanyang UniversityDepartment of Life Sciences, College of Natural Science, Hanyang UniversityDepartment of Genetics, Harvard Medical SchoolDepartment of Oral Biology, Yonsei University, College of DentistryDepartment of Life Sciences, College of Natural Science, Hanyang UniversityDepartment of Life Sciences, College of Natural Science, Hanyang UniversityDepartment of Oral Biology, Yonsei University, College of DentistryDepartment of Genetics, Harvard Medical SchoolDepartment of Life Sciences, College of Natural Science, Hanyang UniversityDepartment of Life Sciences, College of Natural Science, Hanyang UniversityHow the Drosophila lymph gland hemocytes develop and are regulated at a single-cell level is unclear. Here, the authors use single-cell RNA sequencing to show heterogeneity of developing hemocytes in the lymph gland and how they react to wasp infestation, and compare hemocytes from two independent origins.https://doi.org/10.1038/s41467-020-18135-y
spellingShingle Bumsik Cho
Sang-Ho Yoon
Daewon Lee
Ferdinand Koranteng
Sudhir Gopal Tattikota
Nuri Cha
Mingyu Shin
Hobin Do
Yanhui Hu
Sue Young Oh
Daehan Lee
A. Vipin Menon
Seok Jun Moon
Norbert Perrimon
Jin-Wu Nam
Jiwon Shim
Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila
Nature Communications
title Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila
title_full Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila
title_fullStr Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila
title_full_unstemmed Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila
title_short Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila
title_sort single cell transcriptome maps of myeloid blood cell lineages in drosophila
url https://doi.org/10.1038/s41467-020-18135-y
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