Drug-Biopolymer Dispersions: Morphology- and Temperature- Dependent (Anti)Plasticizer Effect of the Drug and Component-Specific Johari–Goldstein Relaxations

Drug-Biopolymer Dispersions: Morphology- and Temperature- Dependent (Anti)Plasticizer Effect of the Drug and Component-Specific Johari–Goldstein Relaxations

Amorphous molecule-macromolecule mixtures are ubiquitous in polymer technology and are one of the most studied routes for the development of amorphous drug formulations. For these applications it is crucial to understand how the preparation method affects the properties of the mixtures. Here, we emp...

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Bibliographic Details
Main Authors: Sofia Valenti, Luis Javier del Valle, Michela Romanini, Meritxell Mitjana, Jordi Puiggalí, Josep Lluís Tamarit, Roberto Macovez
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
amorphous pharmaceuticals
polymer enantiomerism
Valium metabolite
formulation morphology
glass transition
dielectric spectroscopy
Online Access:https://www.mdpi.com/1422-0067/23/5/2456

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