Cordyceps militaris polysaccharides: preparation and topical product application
Abstract Background Topical product derived from the fungus Cordyceps militaris was explored as a feasible method for an industrial practice. Results The mycelium residue of C. militaris that was industrial biotechnological produced was extracted with water at different time conditions under ambient...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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BMC
2023-01-01
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| Series: | Fungal Biology and Biotechnology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40694-023-00150-5 |
| _version_ | 1811176034196783104 |
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| author | Mayuree Kanlayavattanakul Nattaya Lourith |
| author_facet | Mayuree Kanlayavattanakul Nattaya Lourith |
| author_sort | Mayuree Kanlayavattanakul |
| collection | DOAJ |
| description | Abstract Background Topical product derived from the fungus Cordyceps militaris was explored as a feasible method for an industrial practice. Results The mycelium residue of C. militaris that was industrial biotechnological produced was extracted with water at different time conditions under ambient temperature, filtered and lyophilized. The extracts were all light to dark brown powder. The 24 h extraction was significantly (p < 0.01) highest in an extractive yield and total polysaccharides content (TPC) (43.33 ± 0.99% and 144.02 ± 2.06 mg glucose/g crude extract). This extract was proved to be stable following an accelerated stability test with the insignificant (p > 0.05) reduction of TPC (4.95 ± 2.23%). Topical product containing the extract were developed. Skin care preparation containing 0.2% extract was exhibited as the appropriated amount giving the stable cream. The developed C. militaris polysaccharide cream was confirmed safe and gained more than 70% of the overall preferences examined in 20 female volunteers. Conclusions Cordyceps militaris mycelium residue is a beneficial source for pharmaceutical products. The C. militaris polysaccharides extract was prepared and qualified in terms of active content and stability. The extract was shown to be compatible with the available cosmetic ingredients. The safe and preferred C. militaris polysaccharides skin care cosmetics was developed. Accordingly, C. militaris polysaccharides skin care cosmetics that meets all the quality characters which are stable, safe, usable and efficient. |
| first_indexed | 2024-04-10T19:45:28Z |
| format | Article |
| id | doaj.art-a21ab319eecc4a13a3ddea34d59b075a |
| institution | Directory Open Access Journal |
| issn | 2054-3085 |
| language | English |
| last_indexed | 2024-04-10T19:45:28Z |
| publishDate | 2023-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Fungal Biology and Biotechnology |
| spelling | doaj.art-a21ab319eecc4a13a3ddea34d59b075a2023-01-29T12:03:18ZengBMCFungal Biology and Biotechnology2054-30852023-01-011011610.1186/s40694-023-00150-5Cordyceps militaris polysaccharides: preparation and topical product applicationMayuree Kanlayavattanakul0Nattaya Lourith1School of Cosmetic Science, Mae Fah Luang UniversitySchool of Cosmetic Science, Mae Fah Luang UniversityAbstract Background Topical product derived from the fungus Cordyceps militaris was explored as a feasible method for an industrial practice. Results The mycelium residue of C. militaris that was industrial biotechnological produced was extracted with water at different time conditions under ambient temperature, filtered and lyophilized. The extracts were all light to dark brown powder. The 24 h extraction was significantly (p < 0.01) highest in an extractive yield and total polysaccharides content (TPC) (43.33 ± 0.99% and 144.02 ± 2.06 mg glucose/g crude extract). This extract was proved to be stable following an accelerated stability test with the insignificant (p > 0.05) reduction of TPC (4.95 ± 2.23%). Topical product containing the extract were developed. Skin care preparation containing 0.2% extract was exhibited as the appropriated amount giving the stable cream. The developed C. militaris polysaccharide cream was confirmed safe and gained more than 70% of the overall preferences examined in 20 female volunteers. Conclusions Cordyceps militaris mycelium residue is a beneficial source for pharmaceutical products. The C. militaris polysaccharides extract was prepared and qualified in terms of active content and stability. The extract was shown to be compatible with the available cosmetic ingredients. The safe and preferred C. militaris polysaccharides skin care cosmetics was developed. Accordingly, C. militaris polysaccharides skin care cosmetics that meets all the quality characters which are stable, safe, usable and efficient.https://doi.org/10.1186/s40694-023-00150-5Cordyceps militarisPharmaceutical productPolysaccharideTopical productSkin care |
| spellingShingle | Mayuree Kanlayavattanakul Nattaya Lourith Cordyceps militaris polysaccharides: preparation and topical product application Fungal Biology and Biotechnology Cordyceps militaris Pharmaceutical product Polysaccharide Topical product Skin care |
| title | Cordyceps militaris polysaccharides: preparation and topical product application |
| title_full | Cordyceps militaris polysaccharides: preparation and topical product application |
| title_fullStr | Cordyceps militaris polysaccharides: preparation and topical product application |
| title_full_unstemmed | Cordyceps militaris polysaccharides: preparation and topical product application |
| title_short | Cordyceps militaris polysaccharides: preparation and topical product application |
| title_sort | cordyceps militaris polysaccharides preparation and topical product application |
| topic | Cordyceps militaris Pharmaceutical product Polysaccharide Topical product Skin care |
| url | https://doi.org/10.1186/s40694-023-00150-5 |
| work_keys_str_mv | AT mayureekanlayavattanakul cordycepsmilitarispolysaccharidespreparationandtopicalproductapplication AT nattayalourith cordycepsmilitarispolysaccharidespreparationandtopicalproductapplication |