Association between dietary theobromine with depression: a population-based study
Abstract Objective The purpose of this study is to investigate the possible link between dietary theobromine intake and symptoms of depression. Materials and methods These results are based on the responses of 3637 people who took part in the National Health and Nutrition Examination Survey in 2017–...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-12-01
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| Series: | BMC Psychiatry |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12888-022-04415-y |
| _version_ | 1811204144747249664 |
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| author | Xin-yu Li Hui Liu Lu-yu Zhang Xi-tao Yang |
| author_facet | Xin-yu Li Hui Liu Lu-yu Zhang Xi-tao Yang |
| author_sort | Xin-yu Li |
| collection | DOAJ |
| description | Abstract Objective The purpose of this study is to investigate the possible link between dietary theobromine intake and symptoms of depression. Materials and methods These results are based on the responses of 3637 people who took part in the National Health and Nutrition Examination Survey in 2017–2018. Participants' daily theobromine intake was determined using a 24-h food questionnaire from the 2017–2018 cycle. Presence of depression was defined as a score of 5 or above on the Patient Health Questionnaire. Association between theobromine intake and depression was examined using a multivariate logistic regression adjusting for several relevant sociodemographic, lifestyle and health-related factors. Results A total of 6903 participants were included in the study. The results of multivariate logistic regression showed a correlation between depressive symptoms and theobromine intake (OR:1.17, 95%CI:1.02–1.34). Conclusions Our cross-sectional population based study suggests that increased theobromine intake is associated with increased risk for depression. Nevertheless, more investigations are needed to confirm our findings. |
| first_indexed | 2024-04-12T03:07:24Z |
| format | Article |
| id | doaj.art-a2208f35cfdd42aa802642bae131474c |
| institution | Directory Open Access Journal |
| issn | 1471-244X |
| language | English |
| last_indexed | 2024-04-12T03:07:24Z |
| publishDate | 2022-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Psychiatry |
| spelling | doaj.art-a2208f35cfdd42aa802642bae131474c2022-12-22T03:50:28ZengBMCBMC Psychiatry1471-244X2022-12-0122111010.1186/s12888-022-04415-yAssociation between dietary theobromine with depression: a population-based studyXin-yu Li0Hui Liu1Lu-yu Zhang2Xi-tao Yang3Department of Interventional Therapy, Multidisciplinary Team of Vascular Anomalies, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong UniversityDepartment of Nephrology, Shanghai Jiao Tong University Affiliated Sixth People’s HospitalThe Department of Kidney Transplantation, The First Affiliated Hospital of Zhengzhou UniversityDepartment of Interventional Therapy, Multidisciplinary Team of Vascular Anomalies, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong UniversityAbstract Objective The purpose of this study is to investigate the possible link between dietary theobromine intake and symptoms of depression. Materials and methods These results are based on the responses of 3637 people who took part in the National Health and Nutrition Examination Survey in 2017–2018. Participants' daily theobromine intake was determined using a 24-h food questionnaire from the 2017–2018 cycle. Presence of depression was defined as a score of 5 or above on the Patient Health Questionnaire. Association between theobromine intake and depression was examined using a multivariate logistic regression adjusting for several relevant sociodemographic, lifestyle and health-related factors. Results A total of 6903 participants were included in the study. The results of multivariate logistic regression showed a correlation between depressive symptoms and theobromine intake (OR:1.17, 95%CI:1.02–1.34). Conclusions Our cross-sectional population based study suggests that increased theobromine intake is associated with increased risk for depression. Nevertheless, more investigations are needed to confirm our findings.https://doi.org/10.1186/s12888-022-04415-yDepressionTheobromineNHANES |
| spellingShingle | Xin-yu Li Hui Liu Lu-yu Zhang Xi-tao Yang Association between dietary theobromine with depression: a population-based study BMC Psychiatry Depression Theobromine NHANES |
| title | Association between dietary theobromine with depression: a population-based study |
| title_full | Association between dietary theobromine with depression: a population-based study |
| title_fullStr | Association between dietary theobromine with depression: a population-based study |
| title_full_unstemmed | Association between dietary theobromine with depression: a population-based study |
| title_short | Association between dietary theobromine with depression: a population-based study |
| title_sort | association between dietary theobromine with depression a population based study |
| topic | Depression Theobromine NHANES |
| url | https://doi.org/10.1186/s12888-022-04415-y |
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