Diagnostics of Multi Drug Resistant Tuberculosis in Chest Radiographs using Local Textures & Extreme Gradient Boosting

This study attempts to detect and differentiate Multi Drug Resistant (MDR) - Tuberculosis (TB) and Drug Sensitive (DS)-TB Chest Radiographs (CXR) using local texture descriptors and Ensemble Learning method. Studies report that CXR images contain likelihood information of the drug resistance which c...

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Main Authors: Govindarajan Satyavratan, Manuskandan S. R., Swaminathan Ramakrishnan
Format: Article
Language:English
Published: De Gruyter 2023-09-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2023-1181
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author Govindarajan Satyavratan
Manuskandan S. R.
Swaminathan Ramakrishnan
author_facet Govindarajan Satyavratan
Manuskandan S. R.
Swaminathan Ramakrishnan
author_sort Govindarajan Satyavratan
collection DOAJ
description This study attempts to detect and differentiate Multi Drug Resistant (MDR) - Tuberculosis (TB) and Drug Sensitive (DS)-TB Chest Radiographs (CXR) using local texture descriptors and Ensemble Learning method. Studies report that CXR images contain likelihood information of the drug resistance which can be utilized computationally. Initially, CXR images are subjected to lung fields segmentation using Reaction Diffusion Level Set method. Further, Local Directional Texture Pattern (LDTP) features are extracted from the segmented lungs to characterize the localized textural variations. Extreme Gradient Boosting (XGBoost) classifier is employed to differentiate DS-TB and MDR-TB images. The obtained results demonstrate the ability of extracted LDTP features to characterize nonspecific textural inhomogeneities in images by operating on its principal directions. XGBoost algorithm provides maximum accuracy of 93% and true positive rate of 94.6% in detecting MDR-TB. As the proposed study differentiates the MDR-TB condition using CXR images, its computerized diagnostics could be used in the early screening and followup of TB ridden patients for public health infection control in any setting.
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spelling doaj.art-a221a28f36a24d60ac06d5f017e2c9e12023-10-30T07:58:13ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042023-09-019172172410.1515/cdbme-2023-1181Diagnostics of Multi Drug Resistant Tuberculosis in Chest Radiographs using Local Textures & Extreme Gradient BoostingGovindarajan Satyavratan0Manuskandan S. R.1Swaminathan Ramakrishnan2Indian Institute of Technology Madras, Chennai, IndiaKaruvee Innovations Pvt. Ltd., Chennai, IndiaIndian Institute of Technology Madras, Chennai, IndiaThis study attempts to detect and differentiate Multi Drug Resistant (MDR) - Tuberculosis (TB) and Drug Sensitive (DS)-TB Chest Radiographs (CXR) using local texture descriptors and Ensemble Learning method. Studies report that CXR images contain likelihood information of the drug resistance which can be utilized computationally. Initially, CXR images are subjected to lung fields segmentation using Reaction Diffusion Level Set method. Further, Local Directional Texture Pattern (LDTP) features are extracted from the segmented lungs to characterize the localized textural variations. Extreme Gradient Boosting (XGBoost) classifier is employed to differentiate DS-TB and MDR-TB images. The obtained results demonstrate the ability of extracted LDTP features to characterize nonspecific textural inhomogeneities in images by operating on its principal directions. XGBoost algorithm provides maximum accuracy of 93% and true positive rate of 94.6% in detecting MDR-TB. As the proposed study differentiates the MDR-TB condition using CXR images, its computerized diagnostics could be used in the early screening and followup of TB ridden patients for public health infection control in any setting.https://doi.org/10.1515/cdbme-2023-1181tuberculosischest radiographxgboostdrug sensitivedrug resistive
spellingShingle Govindarajan Satyavratan
Manuskandan S. R.
Swaminathan Ramakrishnan
Diagnostics of Multi Drug Resistant Tuberculosis in Chest Radiographs using Local Textures & Extreme Gradient Boosting
Current Directions in Biomedical Engineering
tuberculosis
chest radiograph
xgboost
drug sensitive
drug resistive
title Diagnostics of Multi Drug Resistant Tuberculosis in Chest Radiographs using Local Textures & Extreme Gradient Boosting
title_full Diagnostics of Multi Drug Resistant Tuberculosis in Chest Radiographs using Local Textures & Extreme Gradient Boosting
title_fullStr Diagnostics of Multi Drug Resistant Tuberculosis in Chest Radiographs using Local Textures & Extreme Gradient Boosting
title_full_unstemmed Diagnostics of Multi Drug Resistant Tuberculosis in Chest Radiographs using Local Textures & Extreme Gradient Boosting
title_short Diagnostics of Multi Drug Resistant Tuberculosis in Chest Radiographs using Local Textures & Extreme Gradient Boosting
title_sort diagnostics of multi drug resistant tuberculosis in chest radiographs using local textures extreme gradient boosting
topic tuberculosis
chest radiograph
xgboost
drug sensitive
drug resistive
url https://doi.org/10.1515/cdbme-2023-1181
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AT swaminathanramakrishnan diagnosticsofmultidrugresistanttuberculosisinchestradiographsusinglocaltexturesextremegradientboosting