The genome-wide mutational consequences of DNA hypomethylation
Abstract DNA methylation is important for establishing and maintaining cell identity and for genomic stability. This is achieved by regulating the accessibility of regulatory and transcriptional elements and the compaction of subtelomeric, centromeric, and other inactive genomic regions. Carcinogene...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-04-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-33932-3 |