AMPK Hyper-Activation Alters Fatty Acids Metabolism and Impairs Invasiveness of Trophoblasts in Preeclampsia

AMPK Hyper-Activation Alters Fatty Acids Metabolism and Impairs Invasiveness of Trophoblasts in Preeclampsia

Background/Aims: Preeclampsia (PE) has long been assumed to be an ischemic disease of the placenta, although there is limited evidence as to how the ischemia impacts on the placenta. AMP-activated protein kinase (AMPK) is a key regulator of cellular energy metabolism and plays an important role in a...

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Main Authors: Xiaotao Yang, Ping Xu, Fumei Zhang, Li Zhang, Yangxi Zheng, Mingyu Hu, Lulu Wang, Ting-li Han, Chuan Peng, Lianlian Wang, Li Wen, Yiwen Zeng, Rufei Gao, Yong Xia, Chao Tong, Zhu Yang, Hongbo Qi, Philip N. Baker
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Preeclampsia
AMPK
Placenta
Fatty acids
Trophoblast
Metabolomics
Online Access:https://www.karger.com/Article/FullText/492995

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