Sinoatrial Node Structure, Mechanics, Electrophysiology and the Chronotropic Response to Stretch in Rabbit and Mouse
The rhythmic electrical activity of the heart’s natural pacemaker, the sinoatrial node (SAN), determines cardiac beating rate (BR). SAN electrical activity is tightly controlled by multiple factors, including tissue stretch, which may contribute to adaptation of BR to changes in venous return. In mo...
Main Authors: | Eilidh A. MacDonald, Josef Madl, Joachim Greiner, Ahmed F. Ramadan, Sarah M. Wells, Angelo G. Torrente, Peter Kohl, Eva A. Rog-Zielinska, T. Alexander Quinn |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-07-01
|
Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fphys.2020.00809/full |
Similar Items
-
SWELL signalling in adipocytes: can fat 'feel' fat?
by: Susheel K. Gunasekar, et al.
Published: (2019-01-01) -
The Lectin LecA Sensitizes the Human Stretch-Activated Channel TREK-1 but Not Piezo1 and Binds Selectively to Cardiac Non-myocytes
by: Elisa Darkow, et al.
Published: (2020-05-01) -
Caveolae provide a specialized membrane environment for respiratory syncytial virus assembly
by: Ravi, Laxmi Iyer, et al.
Published: (2017) -
Analysis of the chronotropic effect of acetylcholine on sinoatrial node cells.
by: Zhang, H, et al.
Published: (2002) -
Neurohumoral Control of Sinoatrial Node Activity and Heart Rate: Insight From Experimental Models and Findings From Humans
by: Eilidh A. MacDonald, et al.
Published: (2020-03-01)