Lipid-albumin nanoassemblies co-loaded with borneol and paclitaxel for intracellular drug delivery to C6 glioma cells with P-gp inhibition and its tumor targeting

Lipid-albumin nanoassemblies co-loaded with borneol and paclitaxel for intracellular drug delivery to C6 glioma cells with P-gp inhibition and its tumor targeting

Successful chemotherapy with paclitaxel (PTX) is impeded by multidrug resistance (MDR) in tumor cells. In this study, lipid-albumin nanoassemblies co-loaded with borneol and paclitaxel (BOR/PTX LANs) were prepared to circumvent MDR in C6 glioma cells. The physiochemical properties including particle...

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Bibliographic Details
Main Authors: Bo Tang, Guihua Fang, Ying Gao, Yi Liu, Jinwen Liu, Meijuan Zou, Lihong Wang, Gang Cheng
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Borneol
Paclitaxel
Lipid-albumin nanoassemblies
C6 glioma cells
P-gp inhibition
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087615000392

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