Modulation of T cell metabolism and function through calcium signaling

Modulation of T cell metabolism and function through calcium signaling

As a vital second messenger in the activation of lymphocytes, the divalent cation Ca2+ plays numerous roles in adaptive immune responses. Importantly, Ca2+ signaling is essential for T cell activation, tolerance of self-antigens, and homeostasis. Supporting the essential role of Ca2+ signaling in T...

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Bibliographic Details
Main Authors: Kelley M. Fracchia, Christine ePai, Craig Michael Walsh
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Immunology
Subjects:
Calcium
Immune System
Metabolism
T cells
CRAC
reactive oxygen
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00324/full

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