Emergent dolutegravir resistance in integrase-naïve, treatment experienced patients from Zimbabwe
We report two cases of dolutegravir (DTG) resistance in highly treatment experienced patients. Monitoring for treatment failure and adherence support is important in highly treatment experienced patients taking DTG. What this study adds: Dolutegravir is the mainstay of HIV treatment programmes and...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
AOSIS
2022-10-01
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| Series: | Southern African Journal of HIV Medicine |
| Subjects: | |
| Online Access: | https://sajhivmed.org.za/index.php/hivmed/article/view/1435 |
| _version_ | 1811193324468436992 |
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| author | Linda A. Mandikiyana Chirimuta Margaret J. Pascoe Sara Lowe |
| author_facet | Linda A. Mandikiyana Chirimuta Margaret J. Pascoe Sara Lowe |
| author_sort | Linda A. Mandikiyana Chirimuta |
| collection | DOAJ |
| description | We report two cases of dolutegravir (DTG) resistance in highly treatment experienced patients. Monitoring for treatment failure and adherence support is important in highly treatment experienced patients taking DTG.
What this study adds: Dolutegravir is the mainstay of HIV treatment programmes and emergence of drug resistance to DTG is of public health relevance. |
| first_indexed | 2024-04-12T00:06:32Z |
| format | Article |
| id | doaj.art-a2309c1898e44e92a323dcf9b3467cc5 |
| institution | Directory Open Access Journal |
| issn | 1608-9693 2078-6751 |
| language | English |
| last_indexed | 2024-04-12T00:06:32Z |
| publishDate | 2022-10-01 |
| publisher | AOSIS |
| record_format | Article |
| series | Southern African Journal of HIV Medicine |
| spelling | doaj.art-a2309c1898e44e92a323dcf9b3467cc52022-12-22T03:56:05ZengAOSISSouthern African Journal of HIV Medicine1608-96932078-67512022-10-01231e1e310.4102/sajhivmed.v23i1.1435813Emergent dolutegravir resistance in integrase-naïve, treatment experienced patients from ZimbabweLinda A. Mandikiyana Chirimuta0Margaret J. Pascoe1Sara Lowe2Newlands Clinic, Ruedi Luethy Foundation, HarareNewlands Clinic, Ruedi Luethy Foundation, HarareNewlands Clinic, Ruedi Luethy Foundation, HarareWe report two cases of dolutegravir (DTG) resistance in highly treatment experienced patients. Monitoring for treatment failure and adherence support is important in highly treatment experienced patients taking DTG. What this study adds: Dolutegravir is the mainstay of HIV treatment programmes and emergence of drug resistance to DTG is of public health relevance.https://sajhivmed.org.za/index.php/hivmed/article/view/1435hiv drug resistancedolutegravirintegrase strand inhibitorantiretroviral treatmenthiv |
| spellingShingle | Linda A. Mandikiyana Chirimuta Margaret J. Pascoe Sara Lowe Emergent dolutegravir resistance in integrase-naïve, treatment experienced patients from Zimbabwe Southern African Journal of HIV Medicine hiv drug resistance dolutegravir integrase strand inhibitor antiretroviral treatment hiv |
| title | Emergent dolutegravir resistance in integrase-naïve, treatment experienced patients from Zimbabwe |
| title_full | Emergent dolutegravir resistance in integrase-naïve, treatment experienced patients from Zimbabwe |
| title_fullStr | Emergent dolutegravir resistance in integrase-naïve, treatment experienced patients from Zimbabwe |
| title_full_unstemmed | Emergent dolutegravir resistance in integrase-naïve, treatment experienced patients from Zimbabwe |
| title_short | Emergent dolutegravir resistance in integrase-naïve, treatment experienced patients from Zimbabwe |
| title_sort | emergent dolutegravir resistance in integrase naive treatment experienced patients from zimbabwe |
| topic | hiv drug resistance dolutegravir integrase strand inhibitor antiretroviral treatment hiv |
| url | https://sajhivmed.org.za/index.php/hivmed/article/view/1435 |
| work_keys_str_mv | AT lindaamandikiyanachirimuta emergentdolutegravirresistanceinintegrasenaivetreatmentexperiencedpatientsfromzimbabwe AT margaretjpascoe emergentdolutegravirresistanceinintegrasenaivetreatmentexperiencedpatientsfromzimbabwe AT saralowe emergentdolutegravirresistanceinintegrasenaivetreatmentexperiencedpatientsfromzimbabwe |