Research advances in the treatment of lung diseases based on mesenchymal stem cell exosomes
Exosomes secreted by mesenchymal stem cell(MSC-EXOs)carry lipids,proteins,nucleic acids and other signaling substances, which play an important role in intercellular communication, immune regulation and vascular regeneration. MSC-EXOs in pulmonary hypertension, pulmonary fibrosis and other lung dise...
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| Format: | Article |
| Language: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2023-01-01
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| Series: | Jichu yixue yu linchuang |
| Subjects: | |
| Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-1-192.pdf |
| _version_ | 1797366372378869760 |
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| author | CHEN Lili,SUN Yonghong,LEI Xiaoyan,WANG Jianjun,CHEN Xingxing,BAO Baixin |
| author_facet | CHEN Lili,SUN Yonghong,LEI Xiaoyan,WANG Jianjun,CHEN Xingxing,BAO Baixin |
| author_sort | CHEN Lili,SUN Yonghong,LEI Xiaoyan,WANG Jianjun,CHEN Xingxing,BAO Baixin |
| collection | DOAJ |
| description | Exosomes secreted by mesenchymal stem cell(MSC-EXOs)carry lipids,proteins,nucleic acids and other signaling substances, which play an important role in intercellular communication, immune regulation and vascular regeneration. MSC-EXOs in pulmonary hypertension, pulmonary fibrosis and other lung diseases can improve the function of the lung tissue and treat lung diseases by regulating different signaling pathways, reducing cell inflammatory reaction, regulating immune function, improving the function of mitochondria, promoting angiogenesis, reducing pulmonary vascular remodeling and etc.,which provides new ideas for the treatment of refractory lung diseases in the future. |
| first_indexed | 2024-03-08T17:03:12Z |
| format | Article |
| id | doaj.art-a2317da2f0594d05ac1024b57a21e946 |
| institution | Directory Open Access Journal |
| issn | 1001-6325 |
| language | zho |
| last_indexed | 2024-03-08T17:03:12Z |
| publishDate | 2023-01-01 |
| publisher | Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. |
| record_format | Article |
| series | Jichu yixue yu linchuang |
| spelling | doaj.art-a2317da2f0594d05ac1024b57a21e9462024-01-04T07:27:26ZzhoInstitute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.Jichu yixue yu linchuang1001-63252023-01-0143119219510.16352/j.issn.1001-6325.2023.01.0192Research advances in the treatment of lung diseases based on mesenchymal stem cell exosomesCHEN Lili,SUN Yonghong,LEI Xiaoyan,WANG Jianjun,CHEN Xingxing,BAO Baixin01. First College of Clinical Medicine,Gansu University Traditional Chinese Medicine,Lanzhou 730000;;2. Department of Pediatrics, Gansu Provincial Peoples Hospital,Lanzhou 730000,ChinaExosomes secreted by mesenchymal stem cell(MSC-EXOs)carry lipids,proteins,nucleic acids and other signaling substances, which play an important role in intercellular communication, immune regulation and vascular regeneration. MSC-EXOs in pulmonary hypertension, pulmonary fibrosis and other lung diseases can improve the function of the lung tissue and treat lung diseases by regulating different signaling pathways, reducing cell inflammatory reaction, regulating immune function, improving the function of mitochondria, promoting angiogenesis, reducing pulmonary vascular remodeling and etc.,which provides new ideas for the treatment of refractory lung diseases in the future.http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-1-192.pdfmesenchymal stem cell|exosome|lung disease |
| spellingShingle | CHEN Lili,SUN Yonghong,LEI Xiaoyan,WANG Jianjun,CHEN Xingxing,BAO Baixin Research advances in the treatment of lung diseases based on mesenchymal stem cell exosomes Jichu yixue yu linchuang mesenchymal stem cell|exosome|lung disease |
| title | Research advances in the treatment of lung diseases based on mesenchymal stem cell exosomes |
| title_full | Research advances in the treatment of lung diseases based on mesenchymal stem cell exosomes |
| title_fullStr | Research advances in the treatment of lung diseases based on mesenchymal stem cell exosomes |
| title_full_unstemmed | Research advances in the treatment of lung diseases based on mesenchymal stem cell exosomes |
| title_short | Research advances in the treatment of lung diseases based on mesenchymal stem cell exosomes |
| title_sort | research advances in the treatment of lung diseases based on mesenchymal stem cell exosomes |
| topic | mesenchymal stem cell|exosome|lung disease |
| url | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-1-192.pdf |
| work_keys_str_mv | AT chenlilisunyonghongleixiaoyanwangjianjunchenxingxingbaobaixin researchadvancesinthetreatmentoflungdiseasesbasedonmesenchymalstemcellexosomes |