MPO-ANCA Associated Vasculitis Following COVID-19 Vaccination – A Case Report

Whether autoimmune or rheumatic disease can be precipitated after vaccination is controversial. Only epidemiological studies or clinical trials with an extremely large sample size can allow for a consistent assessment of the relative risk of vaccine-related incidence. Studies with such large sample...

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Main Authors: Mahmoud Khalifa, Yara Adel Altahan, Paavana Varanasi
Format: Article
Language:English
Published: Levy Library Press 2021-05-01
Series:Journal of Scientific Innovation in Medicine
Subjects:
Online Access:https://journalofscientificinnovationinmedicine.org/articles/101
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author Mahmoud Khalifa
Yara Adel Altahan
Paavana Varanasi
author_facet Mahmoud Khalifa
Yara Adel Altahan
Paavana Varanasi
author_sort Mahmoud Khalifa
collection DOAJ
description Whether autoimmune or rheumatic disease can be precipitated after vaccination is controversial. Only epidemiological studies or clinical trials with an extremely large sample size can allow for a consistent assessment of the relative risk of vaccine-related incidence. Studies with such large sample sizes are complex, difficult to perform, and costly, which limit their administration. There exists no minimum criteria for diagnosing vaccine-related autoimmune diseases, this question must be analyzed on a case-by-case basis. Although our report does not prove a causal association between vaccination and vasculitis, it seems possible that in rare cases, vaccination might induce vasculitic disease. While the possibility of autoimmune disease is very real, without vaccinations the SARS-CoV-2 pandemic will spread unchecked, bringing with it a slew of multisystem disorders, including autoimmune diseases both in the present and future ('Table 1, Figures 1, 2').
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spelling doaj.art-a2350a1383034068983fc0bcfd4984c52022-12-21T21:25:05ZengLevy Library PressJournal of Scientific Innovation in Medicine2579-01532021-05-014210.29024/jsim.10182MPO-ANCA Associated Vasculitis Following COVID-19 Vaccination – A Case ReportMahmoud Khalifa0Yara Adel Altahan1Paavana Varanasi2BronxCare Health SystemRoyal College of Surgeons in Ireland, RCSIBronxCare Health SystemWhether autoimmune or rheumatic disease can be precipitated after vaccination is controversial. Only epidemiological studies or clinical trials with an extremely large sample size can allow for a consistent assessment of the relative risk of vaccine-related incidence. Studies with such large sample sizes are complex, difficult to perform, and costly, which limit their administration. There exists no minimum criteria for diagnosing vaccine-related autoimmune diseases, this question must be analyzed on a case-by-case basis. Although our report does not prove a causal association between vaccination and vasculitis, it seems possible that in rare cases, vaccination might induce vasculitic disease. While the possibility of autoimmune disease is very real, without vaccinations the SARS-CoV-2 pandemic will spread unchecked, bringing with it a slew of multisystem disorders, including autoimmune diseases both in the present and future ('Table 1, Figures 1, 2').https://journalofscientificinnovationinmedicine.org/articles/101covid-19 vaccinationmpo-ancavasculitisautoimmunesars-cov-2covid-19
spellingShingle Mahmoud Khalifa
Yara Adel Altahan
Paavana Varanasi
MPO-ANCA Associated Vasculitis Following COVID-19 Vaccination – A Case Report
Journal of Scientific Innovation in Medicine
covid-19 vaccination
mpo-anca
vasculitis
autoimmune
sars-cov-2
covid-19
title MPO-ANCA Associated Vasculitis Following COVID-19 Vaccination – A Case Report
title_full MPO-ANCA Associated Vasculitis Following COVID-19 Vaccination – A Case Report
title_fullStr MPO-ANCA Associated Vasculitis Following COVID-19 Vaccination – A Case Report
title_full_unstemmed MPO-ANCA Associated Vasculitis Following COVID-19 Vaccination – A Case Report
title_short MPO-ANCA Associated Vasculitis Following COVID-19 Vaccination – A Case Report
title_sort mpo anca associated vasculitis following covid 19 vaccination a case report
topic covid-19 vaccination
mpo-anca
vasculitis
autoimmune
sars-cov-2
covid-19
url https://journalofscientificinnovationinmedicine.org/articles/101
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AT yaraadelaltahan mpoancaassociatedvasculitisfollowingcovid19vaccinationacasereport
AT paavanavaranasi mpoancaassociatedvasculitisfollowingcovid19vaccinationacasereport