First Swedish case of fatal equine parasitic encephalitis by Halicephalobus gingivalis
Abstract Background Halicephalobus gingivalis is a nematode with zoonotic potential which can cause fatal opportunistic infections in various mammals. The parasite has never been diagnosed in Sweden, in any species, prior to the presented case. Case presentation An imported 21-year-old Icelandic mar...
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| Format: | Article |
| Language: | English |
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BMC
2023-12-01
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| Series: | Acta Veterinaria Scandinavica |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13028-023-00719-5 |
| _version_ | 1797388146821824512 |
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| author | Karin Maria Olofsson Norbert van de Velde Simone Peletto Barbara Iulini Laura Pratley Behzad Modabberzadeh Emilian Małek Giulio Grandi |
| author_facet | Karin Maria Olofsson Norbert van de Velde Simone Peletto Barbara Iulini Laura Pratley Behzad Modabberzadeh Emilian Małek Giulio Grandi |
| author_sort | Karin Maria Olofsson |
| collection | DOAJ |
| description | Abstract Background Halicephalobus gingivalis is a nematode with zoonotic potential which can cause fatal opportunistic infections in various mammals. The parasite has never been diagnosed in Sweden, in any species, prior to the presented case. Case presentation An imported 21-year-old Icelandic mare developed severe neurological signs. The horse was eventually euthanized and submitted for post-mortem examination where severe lesions in the kidneys were noted. Histopathology revealed the presence of H. gingivalis in both kidneys and the brain. Phylogenetic analysis of the parasite determined it to belong to Lineage 1. Conclusions With the occurrence of H. gingivalis in Sweden, the disease should be added to the list of differential diagnoses in cases with acute onset of neurological disease in both horses and other mammals including humans. |
| first_indexed | 2024-03-08T22:36:37Z |
| format | Article |
| id | doaj.art-a238324ab3214afe8d1d01e14db8df8f |
| institution | Directory Open Access Journal |
| issn | 1751-0147 |
| language | English |
| last_indexed | 2024-03-08T22:36:37Z |
| publishDate | 2023-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Acta Veterinaria Scandinavica |
| spelling | doaj.art-a238324ab3214afe8d1d01e14db8df8f2023-12-17T12:25:31ZengBMCActa Veterinaria Scandinavica1751-01472023-12-016511610.1186/s13028-023-00719-5First Swedish case of fatal equine parasitic encephalitis by Halicephalobus gingivalisKarin Maria Olofsson0Norbert van de Velde1Simone Peletto2Barbara Iulini3Laura Pratley4Behzad Modabberzadeh5Emilian Małek6Giulio Grandi7Department of Pathology and Wildlife Diseases, National Veterinary Institute (SVA)Department of Pathology and Wildlife Diseases, National Veterinary Institute (SVA)Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D’AostaIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D’AostaEvidensia Specialisthästsjukhuset HelsingborgFarm & Animal HealthDepartment of Pathology and Wildlife Diseases, National Veterinary Institute (SVA)Department of Microbiology, National Veterinary Institute (SVA)Abstract Background Halicephalobus gingivalis is a nematode with zoonotic potential which can cause fatal opportunistic infections in various mammals. The parasite has never been diagnosed in Sweden, in any species, prior to the presented case. Case presentation An imported 21-year-old Icelandic mare developed severe neurological signs. The horse was eventually euthanized and submitted for post-mortem examination where severe lesions in the kidneys were noted. Histopathology revealed the presence of H. gingivalis in both kidneys and the brain. Phylogenetic analysis of the parasite determined it to belong to Lineage 1. Conclusions With the occurrence of H. gingivalis in Sweden, the disease should be added to the list of differential diagnoses in cases with acute onset of neurological disease in both horses and other mammals including humans.https://doi.org/10.1186/s13028-023-00719-5Encephalitic and nephritic nematodiasisHorsePhylogenetic analysisZoonosis |
| spellingShingle | Karin Maria Olofsson Norbert van de Velde Simone Peletto Barbara Iulini Laura Pratley Behzad Modabberzadeh Emilian Małek Giulio Grandi First Swedish case of fatal equine parasitic encephalitis by Halicephalobus gingivalis Acta Veterinaria Scandinavica Encephalitic and nephritic nematodiasis Horse Phylogenetic analysis Zoonosis |
| title | First Swedish case of fatal equine parasitic encephalitis by Halicephalobus gingivalis |
| title_full | First Swedish case of fatal equine parasitic encephalitis by Halicephalobus gingivalis |
| title_fullStr | First Swedish case of fatal equine parasitic encephalitis by Halicephalobus gingivalis |
| title_full_unstemmed | First Swedish case of fatal equine parasitic encephalitis by Halicephalobus gingivalis |
| title_short | First Swedish case of fatal equine parasitic encephalitis by Halicephalobus gingivalis |
| title_sort | first swedish case of fatal equine parasitic encephalitis by halicephalobus gingivalis |
| topic | Encephalitic and nephritic nematodiasis Horse Phylogenetic analysis Zoonosis |
| url | https://doi.org/10.1186/s13028-023-00719-5 |
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