Serospatial epidemiology of zoonotic Coxiella burnetii in a cross section of cattle and small ruminants in northern Nigeria.
The persistent and highly transmissible Coxiella burnetii is a neglected infection that negatively affects reproductive parameters of livestock. It is also of zoonotic importance and has been reported to cause devastating human infections globally. Domestic ruminants represent the most frequent sour...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2020-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0240249 |
| _version_ | 1828955105490108416 |
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| author | Nusirat Elelu Adefolake Ayinke Bankole Ramat Jummai Musa Ismail Ayoade Odetokun Musa Rabiu Khalid Talha Biobaku Abdulfatai Aremu Akeem Olayiwola Ahmed Mohammed Ibraheem Ghali Mashood Abiola Raji Ndudim Isaac Ogo Sally Jane Cutler Gabriel Adetunji Taiwo Ogundipe |
| author_facet | Nusirat Elelu Adefolake Ayinke Bankole Ramat Jummai Musa Ismail Ayoade Odetokun Musa Rabiu Khalid Talha Biobaku Abdulfatai Aremu Akeem Olayiwola Ahmed Mohammed Ibraheem Ghali Mashood Abiola Raji Ndudim Isaac Ogo Sally Jane Cutler Gabriel Adetunji Taiwo Ogundipe |
| author_sort | Nusirat Elelu |
| collection | DOAJ |
| description | The persistent and highly transmissible Coxiella burnetii is a neglected infection that negatively affects reproductive parameters of livestock. It is also of zoonotic importance and has been reported to cause devastating human infections globally. Domestic ruminants represent the most frequent source of human infection. Data from Nigeria are very few and outdated. There is a significant gap in up-to-date information on the exposure, spatial distribution and risk factors of infection of this important disease. The exposure to C. burnetii was determined using sensitive serological assays in cattle and small ruminants. A total of 538 animals made up of 268 cattle and 270 small ruminants were sampled from three northern Nigerian states. The proportion of cattle sampled that were seropositive from the study locations were: Kwara 14/90 (15.6%; 95% CI: 8.8-24.7); Plateau 10/106 (9.43%; 95% CI: 4.6-16.7) and Borno 4/72 (5.56%; 95% CI: 1.5-13.6) states. Lower seroprevalence was recorded among the small ruminants sampled, with positives recorded from sheep and goat sampled from only Kwara state 6/184 (3.3%; 95% CI: 1.2-7.0); while none of the small ruminants sampled from Plateau were seropositive. The results of the bivariate analysis showed that none of the tested independent variables (village, age group, sex, breed of cattle, presence of ticks, reproductive status, and management system) were statistically significant factors associated with seropositivity of cattle for antibodies to C. burnetii. Stakeholders involved in animal husbandry should be duly educated on proper disposal of birth products as well as bodily fluids in order to reduce environmental contamination, persistence and human infection. |
| first_indexed | 2024-12-14T07:44:48Z |
| format | Article |
| id | doaj.art-a238dfeba54d4f198832d67f2eed66b0 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-14T07:44:48Z |
| publishDate | 2020-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-a238dfeba54d4f198832d67f2eed66b02022-12-21T23:10:56ZengPublic Library of Science (PLoS)PLoS ONE1932-62032020-01-011510e024024910.1371/journal.pone.0240249Serospatial epidemiology of zoonotic Coxiella burnetii in a cross section of cattle and small ruminants in northern Nigeria.Nusirat EleluAdefolake Ayinke BankoleRamat Jummai MusaIsmail Ayoade OdetokunMusa RabiuKhalid Talha BiobakuAbdulfatai AremuAkeem Olayiwola AhmedMohammed Ibraheem GhaliMashood Abiola RajiNdudim Isaac OgoSally Jane CutlerGabriel Adetunji Taiwo OgundipeThe persistent and highly transmissible Coxiella burnetii is a neglected infection that negatively affects reproductive parameters of livestock. It is also of zoonotic importance and has been reported to cause devastating human infections globally. Domestic ruminants represent the most frequent source of human infection. Data from Nigeria are very few and outdated. There is a significant gap in up-to-date information on the exposure, spatial distribution and risk factors of infection of this important disease. The exposure to C. burnetii was determined using sensitive serological assays in cattle and small ruminants. A total of 538 animals made up of 268 cattle and 270 small ruminants were sampled from three northern Nigerian states. The proportion of cattle sampled that were seropositive from the study locations were: Kwara 14/90 (15.6%; 95% CI: 8.8-24.7); Plateau 10/106 (9.43%; 95% CI: 4.6-16.7) and Borno 4/72 (5.56%; 95% CI: 1.5-13.6) states. Lower seroprevalence was recorded among the small ruminants sampled, with positives recorded from sheep and goat sampled from only Kwara state 6/184 (3.3%; 95% CI: 1.2-7.0); while none of the small ruminants sampled from Plateau were seropositive. The results of the bivariate analysis showed that none of the tested independent variables (village, age group, sex, breed of cattle, presence of ticks, reproductive status, and management system) were statistically significant factors associated with seropositivity of cattle for antibodies to C. burnetii. Stakeholders involved in animal husbandry should be duly educated on proper disposal of birth products as well as bodily fluids in order to reduce environmental contamination, persistence and human infection.https://doi.org/10.1371/journal.pone.0240249 |
| spellingShingle | Nusirat Elelu Adefolake Ayinke Bankole Ramat Jummai Musa Ismail Ayoade Odetokun Musa Rabiu Khalid Talha Biobaku Abdulfatai Aremu Akeem Olayiwola Ahmed Mohammed Ibraheem Ghali Mashood Abiola Raji Ndudim Isaac Ogo Sally Jane Cutler Gabriel Adetunji Taiwo Ogundipe Serospatial epidemiology of zoonotic Coxiella burnetii in a cross section of cattle and small ruminants in northern Nigeria. PLoS ONE |
| title | Serospatial epidemiology of zoonotic Coxiella burnetii in a cross section of cattle and small ruminants in northern Nigeria. |
| title_full | Serospatial epidemiology of zoonotic Coxiella burnetii in a cross section of cattle and small ruminants in northern Nigeria. |
| title_fullStr | Serospatial epidemiology of zoonotic Coxiella burnetii in a cross section of cattle and small ruminants in northern Nigeria. |
| title_full_unstemmed | Serospatial epidemiology of zoonotic Coxiella burnetii in a cross section of cattle and small ruminants in northern Nigeria. |
| title_short | Serospatial epidemiology of zoonotic Coxiella burnetii in a cross section of cattle and small ruminants in northern Nigeria. |
| title_sort | serospatial epidemiology of zoonotic coxiella burnetii in a cross section of cattle and small ruminants in northern nigeria |
| url | https://doi.org/10.1371/journal.pone.0240249 |
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