5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole (DRB) induces apoptosis in breast cancer cells through inhibiting of Mcl-1 expression
Abstract The effective treatment of breast cancer remains a profound clinical challenge, especially due to drug resistance and metastasis which unfortunately arise in many patients. The transcription inhibitor 5,6-dichloro-1-beta-D-ribofuranosyl-benzimidazole (DRB), as a selective inhibitor of cycli...
Main Authors: | Yi-Hsuan Kuo, Tsai-Chun Lai, Chia-Hsin Chang, Han-Ching Hsieh, Feng-Ming Yang, Meng-Chun Hu |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-08-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-39340-x |
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