Action of YM155 on clear cell renal cell carcinoma does not depend on survivin expression levels.

The dioxonapthoimidazolium YM155 is a survivin suppressant which has been investigated as an anticancer agent in clinical trials. Here, we investigated its growth inhibitory properties on a panel of immortalized and patient derived renal cell carcinoma (RCC) cell lines which were either deficient in...

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Autori principali: Mei Yi Sim, Hung Huynh, Mei Lin Go, John Shyi Peng Yuen
Natura: Articolo
Lingua:English
Pubblicazione: Public Library of Science (PLoS) 2017-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC5459331?pdf=render