Action of YM155 on clear cell renal cell carcinoma does not depend on survivin expression levels.

The dioxonapthoimidazolium YM155 is a survivin suppressant which has been investigated as an anticancer agent in clinical trials. Here, we investigated its growth inhibitory properties on a panel of immortalized and patient derived renal cell carcinoma (RCC) cell lines which were either deficient in...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Mei Yi Sim, Hung Huynh, Mei Lin Go, John Shyi Peng Yuen
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Public Library of Science (PLoS) 2017-01-01
Цуврал:PLoS ONE
Онлайн хандалт:http://europepmc.org/articles/PMC5459331?pdf=render