Oncological and functional outcomes for transoral robotic surgery following previous radiation treatment for upper aerodigestive tract head and neck cancers. A French multicenter GETTEC group study
Abstract Background Transoral robotic surgery (TORS) opens new perspectives. We evaluated the outcomes for patients having undergone TORS after previous radiotherapy. Methods A retrospective multicenter study (n = 138) in a previously irradiated area between 2009 and 2020. Survival was assessed with...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-04-01
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| Series: | Cancer Medicine |
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| Online Access: | https://doi.org/10.1002/cam4.7031 |
| _version_ | 1797205656721162240 |
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| author | Olivier Malard Matilde Karakachoff Christophe Ferron Stéphane Hans Sébastien Vergez Renaud Garrel Philippe Gorphe Lionel Ramin Laure Santini Alexandre Villeneuve Audrey Lasne‐Cardon Florent Espitalier Audrey Hounkpatin |
| author_facet | Olivier Malard Matilde Karakachoff Christophe Ferron Stéphane Hans Sébastien Vergez Renaud Garrel Philippe Gorphe Lionel Ramin Laure Santini Alexandre Villeneuve Audrey Lasne‐Cardon Florent Espitalier Audrey Hounkpatin |
| author_sort | Olivier Malard |
| collection | DOAJ |
| description | Abstract Background Transoral robotic surgery (TORS) opens new perspectives. We evaluated the outcomes for patients having undergone TORS after previous radiotherapy. Methods A retrospective multicenter study (n = 138) in a previously irradiated area between 2009 and 2020. Survival was assessed with the Kaplan–Meier method. Prognostic factors were evaluated using a chi‐squared test, Fisher's test, or Wilcoxon's test. Results The median length of hospital stay was 12.5 days. Bleeding was the most frequent postoperative complication (15.2%, n = 22). Prophylactic vessel ligation did not significantly decrease bleeding. Complications were significantly lower for Tis, T1, and N0 tumors. 91.6% (n = 120) of the patients with a perioperative tracheotomy could be decannulated. Larynx was functional for 65.94% of the patients. The median length of follow‐up was 26 months. The 5‐year overall and relapse‐free survival rates were respectively 59.9% and 43.4%. Conclusion Oncological and functional results confirmed the value of TORS as a treatment in previously irradiated area. |
| first_indexed | 2024-04-24T08:54:36Z |
| format | Article |
| id | doaj.art-a23fe56bc8fb4ff2af705dfc7e23e464 |
| institution | Directory Open Access Journal |
| issn | 2045-7634 |
| language | English |
| last_indexed | 2024-04-24T08:54:36Z |
| publishDate | 2024-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cancer Medicine |
| spelling | doaj.art-a23fe56bc8fb4ff2af705dfc7e23e4642024-04-16T08:48:34ZengWileyCancer Medicine2045-76342024-04-01137n/an/a10.1002/cam4.7031Oncological and functional outcomes for transoral robotic surgery following previous radiation treatment for upper aerodigestive tract head and neck cancers. A French multicenter GETTEC group studyOlivier Malard0Matilde Karakachoff1Christophe Ferron2Stéphane Hans3Sébastien Vergez4Renaud Garrel5Philippe Gorphe6Lionel Ramin7Laure Santini8Alexandre Villeneuve9Audrey Lasne‐Cardon10Florent Espitalier11Audrey Hounkpatin12Department of Otolaryngology Head and Neck Surgery Nantes University Hospital Nantes FranceNantes Université, CHU Nantes, Pôle Hospitalo‐Universitaire 11: Santé Publique, Clinique des données, INSERM, CIC 1413 Nantes FranceDepartment of Otolaryngology Head and Neck Surgery Nantes University Hospital Nantes FranceDepartment of Otolaryngology‐Head and Neck Surgery Foch Hospital Suresnes FranceHead and Neck Surgery Department Cancer Institute Toulouse‐Oncopole Toulouse FranceDepartment of Head and Neck Surgery Montpellier Guy De Chauliac University Hospital Montpellier FranceDepartment of Head and Neck Oncology, Gustave Roussy Institute University Paris‐Saclay Villejuif FranceDepartment of Head and Neck Surgery Limoges Dupuytrens University Hospital Limoges FranceENT—Head and Neck Surgery Department, La Conception University Hospital Aix Marseille University Marseille FranceHead and Neck Surgery Department, Georges‐Pompidou European Hospital Paris FranceDepartment of Head and Neck Surgery, François Baclesse Cancer center Normandie University Caen FranceDepartment of Otolaryngology Head and Neck Surgery Nantes University Hospital Nantes FranceDepartment of Otolaryngology Head and Neck Surgery Nantes University Hospital Nantes FranceAbstract Background Transoral robotic surgery (TORS) opens new perspectives. We evaluated the outcomes for patients having undergone TORS after previous radiotherapy. Methods A retrospective multicenter study (n = 138) in a previously irradiated area between 2009 and 2020. Survival was assessed with the Kaplan–Meier method. Prognostic factors were evaluated using a chi‐squared test, Fisher's test, or Wilcoxon's test. Results The median length of hospital stay was 12.5 days. Bleeding was the most frequent postoperative complication (15.2%, n = 22). Prophylactic vessel ligation did not significantly decrease bleeding. Complications were significantly lower for Tis, T1, and N0 tumors. 91.6% (n = 120) of the patients with a perioperative tracheotomy could be decannulated. Larynx was functional for 65.94% of the patients. The median length of follow‐up was 26 months. The 5‐year overall and relapse‐free survival rates were respectively 59.9% and 43.4%. Conclusion Oncological and functional results confirmed the value of TORS as a treatment in previously irradiated area.https://doi.org/10.1002/cam4.7031head and neck cancerradiotherapysquamous cell carcinomatransoral robotic surgery |
| spellingShingle | Olivier Malard Matilde Karakachoff Christophe Ferron Stéphane Hans Sébastien Vergez Renaud Garrel Philippe Gorphe Lionel Ramin Laure Santini Alexandre Villeneuve Audrey Lasne‐Cardon Florent Espitalier Audrey Hounkpatin Oncological and functional outcomes for transoral robotic surgery following previous radiation treatment for upper aerodigestive tract head and neck cancers. A French multicenter GETTEC group study Cancer Medicine head and neck cancer radiotherapy squamous cell carcinoma transoral robotic surgery |
| title | Oncological and functional outcomes for transoral robotic surgery following previous radiation treatment for upper aerodigestive tract head and neck cancers. A French multicenter GETTEC group study |
| title_full | Oncological and functional outcomes for transoral robotic surgery following previous radiation treatment for upper aerodigestive tract head and neck cancers. A French multicenter GETTEC group study |
| title_fullStr | Oncological and functional outcomes for transoral robotic surgery following previous radiation treatment for upper aerodigestive tract head and neck cancers. A French multicenter GETTEC group study |
| title_full_unstemmed | Oncological and functional outcomes for transoral robotic surgery following previous radiation treatment for upper aerodigestive tract head and neck cancers. A French multicenter GETTEC group study |
| title_short | Oncological and functional outcomes for transoral robotic surgery following previous radiation treatment for upper aerodigestive tract head and neck cancers. A French multicenter GETTEC group study |
| title_sort | oncological and functional outcomes for transoral robotic surgery following previous radiation treatment for upper aerodigestive tract head and neck cancers a french multicenter gettec group study |
| topic | head and neck cancer radiotherapy squamous cell carcinoma transoral robotic surgery |
| url | https://doi.org/10.1002/cam4.7031 |
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