Exendin-4-Conjugated Manganese Magnetism-Engineered Iron Oxide Nanoparticles as a Potential Magnetic Resonance Imaging Contrast Agent for Tracking Transplanted β-Cells

Exendin-4-Conjugated Manganese Magnetism-Engineered Iron Oxide Nanoparticles as a Potential Magnetic Resonance Imaging Contrast Agent for Tracking Transplanted β-Cells

To specifically detect and trace transplanted islet β-cells by magnetic resonance imaging (MRI), we conjugated manganese magnetism-engineered iron oxide nanoparticles (MnMEIO NPs) with exendin-4 (Ex4) which specifically binds glucagon-like peptide-1 receptors on the surface of β-cells. The size dist...

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Bibliographic Details
Main Authors: Jyuhn-Huarng Juang, Chia-Rui Shen, Jiun-Jie Wang, Shu-Ting Wu, Sung-Han Lin, Chen-Yi Chen, Chen-Wei Kao, Chen-Ling Chen, Zei-Tsan Tsai, Yun-Ming Wang
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Nanomaterials
Subjects:
islet transplantation
manganese magnetism-engineered iron oxide nanoparticles
exendin-4
magnetic resonance images
Online Access:https://www.mdpi.com/2079-4991/11/11/3145

Internet

https://www.mdpi.com/2079-4991/11/11/3145

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