The synaptonemal complex protein Zip1 promotes bi-orientation of centromeres at meiosis I.

In meiosis I, homologous chromosomes become paired and then separate from one another to opposite poles of the spindle. In humans, errors in this process are a leading cause of birth defects, mental retardation, and infertility. In most organisms, crossing-over, or exchange, between the homologous p...

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Main Authors: Mara N Gladstone, David Obeso, Hoa Chuong, Dean S Dawson
格式: 文件
语言:English
出版: Public Library of Science (PLoS) 2009-12-01
丛编:PLoS Genetics
在线阅读:http://europepmc.org/articles/PMC2781170?pdf=render