Case Report: Secondary Hemophagocytic Lymphohistiocytosis With Disseminated Infection in Chronic Granulomatous Disease—A Serious Cause of Mortality

Case Report: Secondary Hemophagocytic Lymphohistiocytosis With Disseminated Infection in Chronic Granulomatous Disease—A Serious Cause of Mortality

Chronic granulomatous disease (CGD) is a primary immune deficiency due to defects in phagocyte respiratory burst leading to severe and life-threatening infections. Patients with CGD also suffer from disorders of inflammation and immune dysregulation including colitis and granulomatous lung disease,...

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Main Authors: Jacqueline D. Squire, Stephanie N. Vazquez, Angela Chan, Michele E. Smith, Deepak Chellapandian, Laura Vose, Beatriz Teppa, I. Celine Hanson, Ivan K. Chinn, Lisa Forbes-Satter, Filiz O. Seeborg, Sarah K. Nicholas, Caridad A. Martinez, Carl E. Allen, Thomas J. Connors, Prakash Satwani, Maria Shtessel, Hanadys Ale, Lenora M. Noroski, Nicholas L. Rider, Joshua D. Milner, Jennifer W. Leiding
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
chronic granulomatous disease
hemophagocytic lymphohistiocytosis
sepsis
inflammation
case report
infection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.581475/full

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