Role of TM3 in claudin-15 strand flexibility: A molecular dynamics study

Claudins are cell-cell adhesion proteins within tight junctions that connect epithelial cells together. Claudins polymerize into a network of strand-like structures within the membrane of adjoining cells and create ion channels that control paracellular permeability to water and small molecules. Tig...

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Bibliographic Details
Main Authors: Shadi Fuladi, Sarah McGuinness, Fatemeh Khalili-Araghi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.964877/full