Willingness to Self-Collect a Sample for HPV-Based Cervical Cancer Screening in a Well-Screened Cohort: HPV FOCAL Survey Results
Self-collection may provide an opportunity for innovation within population-based human papillomavirus (HPV) cervical cancer screening programs by providing an alternative form of engagement for all individuals. The primary objective was to determine willingness to self-collect a vaginal sample for...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-05-01
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| Series: | Current Oncology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1718-7729/29/6/308 |
| _version_ | 1827661079984996352 |
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| author | Anne Lesack Laurie W. Smith C. Sarai Racey Lovedeep Gondara Mel Krajden Marette Lee Ruth Elwood Martin Gavin Stuart Stuart Peacock Eduardo L. Franco Dirk van Niekerk Gina S. Ogilvie |
| author_facet | Anne Lesack Laurie W. Smith C. Sarai Racey Lovedeep Gondara Mel Krajden Marette Lee Ruth Elwood Martin Gavin Stuart Stuart Peacock Eduardo L. Franco Dirk van Niekerk Gina S. Ogilvie |
| author_sort | Anne Lesack |
| collection | DOAJ |
| description | Self-collection may provide an opportunity for innovation within population-based human papillomavirus (HPV) cervical cancer screening programs by providing an alternative form of engagement for all individuals. The primary objective was to determine willingness to self-collect a vaginal sample for primary HPV screening and factors that impact willingness in individuals who participated in the Human Papillomavirus For Cervical Cancer (HPV FOCAL) screening trial, a large randomized controlled cervical screening trial. A cross-sectional online survey was distributed between 2017 and 2018 to 13,176 eligible participants exiting the FOCAL trial. Bivariate and multivariable logistic regression assessed factors that influence willingness to self-collect on 4945 respondents. Overall, 52.1% of respondents indicated willingness to self-collect an HPV sample. In multivariable analysis, the odds of willingness to self-collect were significantly higher in participants who agreed that screening with an HPV test instead of a Pap test was acceptable to them (odds ratio (OR): 1.45 (95% confidence interval (CI): 1.15, 1.82), those who indicated that collecting their own HPV sample was acceptable to them (<i>p</i> < 0.001), and those with higher educational ascertainment (OR: 1.31, 95% CI: 1.12, 1.54). The findings offer insight into the intentions to self-collect in those already engaged in screening, and can inform cervical cancer screening programs interested in offering alternative approaches to HPV-based screening. |
| first_indexed | 2024-03-10T00:02:32Z |
| format | Article |
| id | doaj.art-a248b86eb9514a4c8401089b7f2c20dc |
| institution | Directory Open Access Journal |
| issn | 1198-0052 1718-7729 |
| language | English |
| last_indexed | 2024-03-10T00:02:32Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj.art-a248b86eb9514a4c8401089b7f2c20dc2023-11-23T16:13:39ZengMDPI AGCurrent Oncology1198-00521718-77292022-05-012963860386910.3390/curroncol29060308Willingness to Self-Collect a Sample for HPV-Based Cervical Cancer Screening in a Well-Screened Cohort: HPV FOCAL Survey ResultsAnne Lesack0Laurie W. Smith1C. Sarai Racey2Lovedeep Gondara3Mel Krajden4Marette Lee5Ruth Elwood Martin6Gavin Stuart7Stuart Peacock8Eduardo L. Franco9Dirk van Niekerk10Gina S. Ogilvie11Faculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z4, CanadaCancer Control Research, BC Cancer, Vancouver, BC V5Z 1L3, CanadaFaculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z4, CanadaCancer Surveillance and Outcomes, BC Cancer, Vancouver, BC V5Z 4E6, CanadaFaculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z4, CanadaFaculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z4, CanadaFaculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z4, CanadaFaculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z4, CanadaCancer Control Research, BC Cancer, Vancouver, BC V5Z 1L3, CanadaDivision of Cancer Epidemiology, Faculty of Medicine, McGill University, Montreal, QC H4A 3T2, CanadaFaculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z4, CanadaFaculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z4, CanadaSelf-collection may provide an opportunity for innovation within population-based human papillomavirus (HPV) cervical cancer screening programs by providing an alternative form of engagement for all individuals. The primary objective was to determine willingness to self-collect a vaginal sample for primary HPV screening and factors that impact willingness in individuals who participated in the Human Papillomavirus For Cervical Cancer (HPV FOCAL) screening trial, a large randomized controlled cervical screening trial. A cross-sectional online survey was distributed between 2017 and 2018 to 13,176 eligible participants exiting the FOCAL trial. Bivariate and multivariable logistic regression assessed factors that influence willingness to self-collect on 4945 respondents. Overall, 52.1% of respondents indicated willingness to self-collect an HPV sample. In multivariable analysis, the odds of willingness to self-collect were significantly higher in participants who agreed that screening with an HPV test instead of a Pap test was acceptable to them (odds ratio (OR): 1.45 (95% confidence interval (CI): 1.15, 1.82), those who indicated that collecting their own HPV sample was acceptable to them (<i>p</i> < 0.001), and those with higher educational ascertainment (OR: 1.31, 95% CI: 1.12, 1.54). The findings offer insight into the intentions to self-collect in those already engaged in screening, and can inform cervical cancer screening programs interested in offering alternative approaches to HPV-based screening.https://www.mdpi.com/1718-7729/29/6/308human papillomavirusHPVHPV self-samplingHPV testing for cervix screeningattitudes and acceptance HPV self-sampling |
| spellingShingle | Anne Lesack Laurie W. Smith C. Sarai Racey Lovedeep Gondara Mel Krajden Marette Lee Ruth Elwood Martin Gavin Stuart Stuart Peacock Eduardo L. Franco Dirk van Niekerk Gina S. Ogilvie Willingness to Self-Collect a Sample for HPV-Based Cervical Cancer Screening in a Well-Screened Cohort: HPV FOCAL Survey Results Current Oncology human papillomavirus HPV HPV self-sampling HPV testing for cervix screening attitudes and acceptance HPV self-sampling |
| title | Willingness to Self-Collect a Sample for HPV-Based Cervical Cancer Screening in a Well-Screened Cohort: HPV FOCAL Survey Results |
| title_full | Willingness to Self-Collect a Sample for HPV-Based Cervical Cancer Screening in a Well-Screened Cohort: HPV FOCAL Survey Results |
| title_fullStr | Willingness to Self-Collect a Sample for HPV-Based Cervical Cancer Screening in a Well-Screened Cohort: HPV FOCAL Survey Results |
| title_full_unstemmed | Willingness to Self-Collect a Sample for HPV-Based Cervical Cancer Screening in a Well-Screened Cohort: HPV FOCAL Survey Results |
| title_short | Willingness to Self-Collect a Sample for HPV-Based Cervical Cancer Screening in a Well-Screened Cohort: HPV FOCAL Survey Results |
| title_sort | willingness to self collect a sample for hpv based cervical cancer screening in a well screened cohort hpv focal survey results |
| topic | human papillomavirus HPV HPV self-sampling HPV testing for cervix screening attitudes and acceptance HPV self-sampling |
| url | https://www.mdpi.com/1718-7729/29/6/308 |
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