DNA Ligase C and Prim-PolC participate in base excision repair in mycobacteria

Ligase D is a conserved DNA repair protein complex that repairs double-strand breaks in stationary phase prokaryotes. Here the authors show that orthologous Ligase C has a role in base excision repair during stationary phase.

Bibliographic Details
Main Authors: Przemysław Płociński, Nigel C. Brissett, Julie Bianchi, Anna Brzostek, Małgorzata Korycka-Machała, Andrzej Dziembowski, Jarosław Dziadek, Aidan J. Doherty
Format: Article
Language:English
Published: Nature Portfolio 2017-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01365-y
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author Przemysław Płociński
Nigel C. Brissett
Julie Bianchi
Anna Brzostek
Małgorzata Korycka-Machała
Andrzej Dziembowski
Jarosław Dziadek
Aidan J. Doherty
author_facet Przemysław Płociński
Nigel C. Brissett
Julie Bianchi
Anna Brzostek
Małgorzata Korycka-Machała
Andrzej Dziembowski
Jarosław Dziadek
Aidan J. Doherty
author_sort Przemysław Płociński
collection DOAJ
description Ligase D is a conserved DNA repair protein complex that repairs double-strand breaks in stationary phase prokaryotes. Here the authors show that orthologous Ligase C has a role in base excision repair during stationary phase.
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spelling doaj.art-a24b3e4c125948e386f4a4cf060196402022-12-21T20:29:31ZengNature PortfolioNature Communications2041-17232017-11-018111210.1038/s41467-017-01365-yDNA Ligase C and Prim-PolC participate in base excision repair in mycobacteriaPrzemysław Płociński0Nigel C. Brissett1Julie Bianchi2Anna Brzostek3Małgorzata Korycka-Machała4Andrzej Dziembowski5Jarosław Dziadek6Aidan J. Doherty7Genome Damage and Stability Centre, School of Life Sciences, University of SussexGenome Damage and Stability Centre, School of Life Sciences, University of SussexGenome Damage and Stability Centre, School of Life Sciences, University of SussexInstitute of Medical Biology, Polish Academy of SciencesInstitute of Medical Biology, Polish Academy of SciencesInstitute of Biochemistry and Biophysics, Polish Academy of SciencesInstitute of Medical Biology, Polish Academy of SciencesGenome Damage and Stability Centre, School of Life Sciences, University of SussexLigase D is a conserved DNA repair protein complex that repairs double-strand breaks in stationary phase prokaryotes. Here the authors show that orthologous Ligase C has a role in base excision repair during stationary phase.https://doi.org/10.1038/s41467-017-01365-y
spellingShingle Przemysław Płociński
Nigel C. Brissett
Julie Bianchi
Anna Brzostek
Małgorzata Korycka-Machała
Andrzej Dziembowski
Jarosław Dziadek
Aidan J. Doherty
DNA Ligase C and Prim-PolC participate in base excision repair in mycobacteria
Nature Communications
title DNA Ligase C and Prim-PolC participate in base excision repair in mycobacteria
title_full DNA Ligase C and Prim-PolC participate in base excision repair in mycobacteria
title_fullStr DNA Ligase C and Prim-PolC participate in base excision repair in mycobacteria
title_full_unstemmed DNA Ligase C and Prim-PolC participate in base excision repair in mycobacteria
title_short DNA Ligase C and Prim-PolC participate in base excision repair in mycobacteria
title_sort dna ligase c and prim polc participate in base excision repair in mycobacteria
url https://doi.org/10.1038/s41467-017-01365-y
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