Beneficial and detrimental genes in the cellular response to replication arrest.

Beneficial and detrimental genes in the cellular response to replication arrest.

DNA replication is essential for all living organisms. Several events can disrupt replication, including DNA damage (e.g., pyrimidine dimers, crosslinking) and so-called "roadblocks" (e.g., DNA-binding proteins or transcription). Bacteria have several well-characterized mechanisms for repa...

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Bibliographic Details
Main Authors: Luciane Schons-Fonseca, Milena D Lazova, Janet L Smith, Mary E Anderson, Alan D Grossman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-12-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010564

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