Fluids and barriers of the CNS: a historical viewpoint
<p>Abstract</p> <p>Tracing the exact origins of modern science can be a difficult but rewarding pursuit. It is possible for the astute reader to follow the background of any subject through the many important surviving texts from the classical and ancient world. While empirical inv...
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| Format: | Article |
| Language: | English |
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BMC
2011-01-01
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| Series: | Fluids and Barriers of the CNS |
| Online Access: | http://www.fluidsbarrierscns.com/content/8/1/2 |
| _version_ | 1811247438896300032 |
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| author | Liddelow Shane A |
| author_facet | Liddelow Shane A |
| author_sort | Liddelow Shane A |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Tracing the exact origins of modern science can be a difficult but rewarding pursuit. It is possible for the astute reader to follow the background of any subject through the many important surviving texts from the classical and ancient world. While empirical investigations have been described by many since the time of Aristotle and scientific methods have been employed since the Middle Ages, the beginnings of modern science are generally accepted to have originated during the 'scientific revolution' of the 16<sup>th </sup>and 17<sup>th </sup>centuries in Europe. The scientific method is so fundamental to modern science that some philosophers consider earlier investigations as 'pre-science'. Notwithstanding this, the insight that can be gained from the study of the beginnings of a subject can prove important in the understanding of work more recently completed. As this journal undergoes an expansion in focus and nomenclature from cerebrospinal fluid (CSF) into all barriers of the central nervous system (CNS), this review traces the history of both the blood-CSF and blood-brain barriers from as early as it was possible to find references, to the time when modern concepts were established at the beginning of the 20<sup>th </sup>century.</p> |
| first_indexed | 2024-04-12T15:08:51Z |
| format | Article |
| id | doaj.art-a24cc36353f84cad8dee3de20d2f4135 |
| institution | Directory Open Access Journal |
| issn | 2045-8118 |
| language | English |
| last_indexed | 2024-04-12T15:08:51Z |
| publishDate | 2011-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Fluids and Barriers of the CNS |
| spelling | doaj.art-a24cc36353f84cad8dee3de20d2f41352022-12-22T03:27:50ZengBMCFluids and Barriers of the CNS2045-81182011-01-0181210.1186/2045-8118-8-2Fluids and barriers of the CNS: a historical viewpointLiddelow Shane A<p>Abstract</p> <p>Tracing the exact origins of modern science can be a difficult but rewarding pursuit. It is possible for the astute reader to follow the background of any subject through the many important surviving texts from the classical and ancient world. While empirical investigations have been described by many since the time of Aristotle and scientific methods have been employed since the Middle Ages, the beginnings of modern science are generally accepted to have originated during the 'scientific revolution' of the 16<sup>th </sup>and 17<sup>th </sup>centuries in Europe. The scientific method is so fundamental to modern science that some philosophers consider earlier investigations as 'pre-science'. Notwithstanding this, the insight that can be gained from the study of the beginnings of a subject can prove important in the understanding of work more recently completed. As this journal undergoes an expansion in focus and nomenclature from cerebrospinal fluid (CSF) into all barriers of the central nervous system (CNS), this review traces the history of both the blood-CSF and blood-brain barriers from as early as it was possible to find references, to the time when modern concepts were established at the beginning of the 20<sup>th </sup>century.</p>http://www.fluidsbarrierscns.com/content/8/1/2 |
| spellingShingle | Liddelow Shane A Fluids and barriers of the CNS: a historical viewpoint Fluids and Barriers of the CNS |
| title | Fluids and barriers of the CNS: a historical viewpoint |
| title_full | Fluids and barriers of the CNS: a historical viewpoint |
| title_fullStr | Fluids and barriers of the CNS: a historical viewpoint |
| title_full_unstemmed | Fluids and barriers of the CNS: a historical viewpoint |
| title_short | Fluids and barriers of the CNS: a historical viewpoint |
| title_sort | fluids and barriers of the cns a historical viewpoint |
| url | http://www.fluidsbarrierscns.com/content/8/1/2 |
| work_keys_str_mv | AT liddelowshanea fluidsandbarriersofthecnsahistoricalviewpoint |