Effect of six weeks of interval training and curcumin consumption on apolipoprotein A and B in diabetic male rats
The present study was conducted to investigate the effect of six weeks of intermittent exercise and curcumin consumption on plasma Apo A and Apo B concentrations in male Wistar rats. 30 male Wistar rats were randomly divided into six groups (5 rats in each group): control, diabetic, healthy intermit...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
JEOCT publisher
2023-06-01
|
| Series: | Journal of Exercise & Organ Cross Talk |
| Subjects: | |
| Online Access: | https://www.jeoct.com/article_172267_93c6eba8b8ebd097372c9d2e5ff29d0e.pdf |
| _version_ | 1797405785756532736 |
|---|---|
| author | Negar Soleimani Mohammad Gallehdari Reza Sheikh |
| author_facet | Negar Soleimani Mohammad Gallehdari Reza Sheikh |
| author_sort | Negar Soleimani |
| collection | DOAJ |
| description | The present study was conducted to investigate the effect of six weeks of intermittent exercise and curcumin consumption on plasma Apo A and Apo B concentrations in male Wistar rats. 30 male Wistar rats were randomly divided into six groups (5 rats in each group): control, diabetic, healthy intermittent exercise, intermittent exercise diabetes, curcumin diabetes and curcumin exercise diabetes. Diabetes was induced by intraperitoneal injection of streptozotocin poison (50 mg/kg). Intermittent training consisted of 5-12 bouts of intense work (75 to 100% of maximum speed) of 60 seconds with active rest intervals of 75 seconds, six days a week for six weeks. Curcumin was fed to animals by gavage at a dose of 50 mg per kilogram of body weight. The results demonstrated that diabetes induction significantly decreased plasma Apo A concentration (p≤0.01) and increased plasma Apo B concentration (p≤0.01). Intermittent training caused a significant increase in Apo A and a significant decrease in Apo B plasma in diabetic rats. Also, it was found that six weeks of curcumin consumption significantly increased the concentration of Apo A in plasma and decreased the concentration of Apo B and the ratio of Apo B to Apo A (p≤0.01). At end, the results of the present study showed that intermittent exercise, curcumin and the combination of two interventions improve the disorders caused by diabetes in apolipoproteins. |
| first_indexed | 2024-03-09T03:15:10Z |
| format | Article |
| id | doaj.art-a253409c945a45929db53c1ec413626a |
| institution | Directory Open Access Journal |
| issn | 2783-2074 |
| language | English |
| last_indexed | 2024-03-09T03:15:10Z |
| publishDate | 2023-06-01 |
| publisher | JEOCT publisher |
| record_format | Article |
| series | Journal of Exercise & Organ Cross Talk |
| spelling | doaj.art-a253409c945a45929db53c1ec413626a2023-12-03T15:27:34ZengJEOCT publisherJournal of Exercise & Organ Cross Talk2783-20742023-06-0132738010.22034/jeoct.2023.400236.1084172267Effect of six weeks of interval training and curcumin consumption on apolipoprotein A and B in diabetic male ratsNegar Soleimani0Mohammad Gallehdari1Reza Sheikh2Master's Degree in Sports Physiology, Sports Nutrition, Faculty of Physical Education, Islamic Azad University, Ahvaz Branch, Iran.Ph.D. in Biochemistry and Sports Metabolism, Department of Physical Education, Faculty of Humanities, Islamic Azad University, Ahvaz Branch, Iran.PhD student in sports physiology, Faculty of Sports Sciences, Shahid Chamran University of Ahvaz, Ahvaz, Iran.The present study was conducted to investigate the effect of six weeks of intermittent exercise and curcumin consumption on plasma Apo A and Apo B concentrations in male Wistar rats. 30 male Wistar rats were randomly divided into six groups (5 rats in each group): control, diabetic, healthy intermittent exercise, intermittent exercise diabetes, curcumin diabetes and curcumin exercise diabetes. Diabetes was induced by intraperitoneal injection of streptozotocin poison (50 mg/kg). Intermittent training consisted of 5-12 bouts of intense work (75 to 100% of maximum speed) of 60 seconds with active rest intervals of 75 seconds, six days a week for six weeks. Curcumin was fed to animals by gavage at a dose of 50 mg per kilogram of body weight. The results demonstrated that diabetes induction significantly decreased plasma Apo A concentration (p≤0.01) and increased plasma Apo B concentration (p≤0.01). Intermittent training caused a significant increase in Apo A and a significant decrease in Apo B plasma in diabetic rats. Also, it was found that six weeks of curcumin consumption significantly increased the concentration of Apo A in plasma and decreased the concentration of Apo B and the ratio of Apo B to Apo A (p≤0.01). At end, the results of the present study showed that intermittent exercise, curcumin and the combination of two interventions improve the disorders caused by diabetes in apolipoproteins.https://www.jeoct.com/article_172267_93c6eba8b8ebd097372c9d2e5ff29d0e.pdfapolipoproteincurcumindiabetesinterval training |
| spellingShingle | Negar Soleimani Mohammad Gallehdari Reza Sheikh Effect of six weeks of interval training and curcumin consumption on apolipoprotein A and B in diabetic male rats Journal of Exercise & Organ Cross Talk apolipoprotein curcumin diabetes interval training |
| title | Effect of six weeks of interval training and curcumin consumption on apolipoprotein A and B in diabetic male rats |
| title_full | Effect of six weeks of interval training and curcumin consumption on apolipoprotein A and B in diabetic male rats |
| title_fullStr | Effect of six weeks of interval training and curcumin consumption on apolipoprotein A and B in diabetic male rats |
| title_full_unstemmed | Effect of six weeks of interval training and curcumin consumption on apolipoprotein A and B in diabetic male rats |
| title_short | Effect of six weeks of interval training and curcumin consumption on apolipoprotein A and B in diabetic male rats |
| title_sort | effect of six weeks of interval training and curcumin consumption on apolipoprotein a and b in diabetic male rats |
| topic | apolipoprotein curcumin diabetes interval training |
| url | https://www.jeoct.com/article_172267_93c6eba8b8ebd097372c9d2e5ff29d0e.pdf |
| work_keys_str_mv | AT negarsoleimani effectofsixweeksofintervaltrainingandcurcuminconsumptiononapolipoproteinaandbindiabeticmalerats AT mohammadgallehdari effectofsixweeksofintervaltrainingandcurcuminconsumptiononapolipoproteinaandbindiabeticmalerats AT rezasheikh effectofsixweeksofintervaltrainingandcurcuminconsumptiononapolipoproteinaandbindiabeticmalerats |