Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception.

Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception.

The ability to perceive noxious stimuli is critical for an animal's survival in the face of environmental danger, and thus pain perception is likely to be under stringent evolutionary pressure. Using a neuronal-specific RNAi knock-down strategy in adult Drosophila, we recently completed a genom...

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Bibliographic Details
Main Authors: G Gregory Neely, Shuan Rao, Michael Costigan, Norbert Mair, Ildiko Racz, Giedre Milinkeviciute, Arabella Meixner, Swetha Nayanala, Robert S Griffin, Inna Belfer, Feng Dai, Shad Smith, Luda Diatchenko, Stefano Marengo, Bernhard J Haubner, Maria Novatchkova, Dustin Gibson, William Maixner, J Andrew Pospisilik, Emilio Hirsch, Ian Q Whishaw, Andreas Zimmer, Vaijayanti Gupta, Junko Sasaki, Yasunori Kanaho, Takehiko Sasaki, Michaela Kress, Clifford J Woolf, Josef M Penninger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3516557?pdf=render

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