Stripping of membranes versus vaginal misoprostol in induction of labor
Background The objective of this study was to evaluate the safety and efficacy of membrane stripping and vaginal misoprostol in the induction of labor in low-risk patients at term pregnancy (38–40 gestational weeks). Aim This study was done to compare the efficacy and safety of the two techniques fo...
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| Format: | Article |
| Language: | English |
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General Organization of Teaching Hospitals and Institutes
2019-01-01
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| Series: | Journal of Medicine in Scientific Research |
| Subjects: | |
| Online Access: | http://www.jmsr.eg.net/article.asp?issn=2537-091X;year=2019;volume=2;issue=2;spage=174;epage=179;aulast=Kamal |
| _version_ | 1797227308785860608 |
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| author | Hesham M Kamal Azza M Youssef Azza Elias |
| author_facet | Hesham M Kamal Azza M Youssef Azza Elias |
| author_sort | Hesham M Kamal |
| collection | DOAJ |
| description | Background
The objective of this study was to evaluate the safety and efficacy of membrane stripping and vaginal misoprostol in the induction of labor in low-risk patients at term pregnancy (38–40 gestational weeks).
Aim
This study was done to compare the efficacy and safety of the two techniques for cervical ripening/labor induction by stripping of membranes and low-dose vaginal misoprostol on the outcome of labor induction in singleton pregnancies between 38 and 40 weeks.
Patients and methods
This prospective study was conducted for 9 months. The study included 100 women divided randomly into two groups: group I (n = 50) in which stripping of membranes was performed and group II (n = 50) which received intravaginal misoprostol. In group I, stripping of membranes was performed to be repeated after 48 h then followed up within 72 h of the first visit. In group II, patients received 25 μg vaginal misoprostol tablets every 6 h with a maximum of four doses after admission for follow-up of fetal well-being and observations of the route of delivery and indication of cesarean section. Time interval from the start of induction to the delivery time and need for oxytocin augmentation and labor complications were observed. Outcome data as fetal weight, Apgar scores at 1 and 5 min, and need for admission to neonatal ICU were recorded.
Results
Stripping of membranes is as effective as vaginal misoprostol, but the induction-delivery interval was significantly lower in misoprostol. There were no statistically significant differences between the two groups in the results of neonatal outcome.
Conclusion
Both methods were effective and safe in the induction of labor; however, misoprostol needs hospital admission, with no increases in the risk of neonatal outcome and minimal adverse effects. |
| first_indexed | 2024-04-24T14:38:45Z |
| format | Article |
| id | doaj.art-a257f2deeecd4a16bbb0c6fb3661e740 |
| institution | Directory Open Access Journal |
| issn | 2537-091X 2537-0928 |
| language | English |
| last_indexed | 2024-04-24T14:38:45Z |
| publishDate | 2019-01-01 |
| publisher | General Organization of Teaching Hospitals and Institutes |
| record_format | Article |
| series | Journal of Medicine in Scientific Research |
| spelling | doaj.art-a257f2deeecd4a16bbb0c6fb3661e7402024-04-02T22:58:27ZengGeneral Organization of Teaching Hospitals and InstitutesJournal of Medicine in Scientific Research2537-091X2537-09282019-01-012217417910.4103/JMISR.JMISR_31_19Stripping of membranes versus vaginal misoprostol in induction of laborHesham M KamalAzza M YoussefAzza EliasBackground The objective of this study was to evaluate the safety and efficacy of membrane stripping and vaginal misoprostol in the induction of labor in low-risk patients at term pregnancy (38–40 gestational weeks). Aim This study was done to compare the efficacy and safety of the two techniques for cervical ripening/labor induction by stripping of membranes and low-dose vaginal misoprostol on the outcome of labor induction in singleton pregnancies between 38 and 40 weeks. Patients and methods This prospective study was conducted for 9 months. The study included 100 women divided randomly into two groups: group I (n = 50) in which stripping of membranes was performed and group II (n = 50) which received intravaginal misoprostol. In group I, stripping of membranes was performed to be repeated after 48 h then followed up within 72 h of the first visit. In group II, patients received 25 μg vaginal misoprostol tablets every 6 h with a maximum of four doses after admission for follow-up of fetal well-being and observations of the route of delivery and indication of cesarean section. Time interval from the start of induction to the delivery time and need for oxytocin augmentation and labor complications were observed. Outcome data as fetal weight, Apgar scores at 1 and 5 min, and need for admission to neonatal ICU were recorded. Results Stripping of membranes is as effective as vaginal misoprostol, but the induction-delivery interval was significantly lower in misoprostol. There were no statistically significant differences between the two groups in the results of neonatal outcome. Conclusion Both methods were effective and safe in the induction of labor; however, misoprostol needs hospital admission, with no increases in the risk of neonatal outcome and minimal adverse effects.http://www.jmsr.eg.net/article.asp?issn=2537-091X;year=2019;volume=2;issue=2;spage=174;epage=179;aulast=Kamalinduction-delivery intervalprolonged gestationstripping of membranesvaginal misoprostol |
| spellingShingle | Hesham M Kamal Azza M Youssef Azza Elias Stripping of membranes versus vaginal misoprostol in induction of labor Journal of Medicine in Scientific Research induction-delivery interval prolonged gestation stripping of membranes vaginal misoprostol |
| title | Stripping of membranes versus vaginal misoprostol in induction of labor |
| title_full | Stripping of membranes versus vaginal misoprostol in induction of labor |
| title_fullStr | Stripping of membranes versus vaginal misoprostol in induction of labor |
| title_full_unstemmed | Stripping of membranes versus vaginal misoprostol in induction of labor |
| title_short | Stripping of membranes versus vaginal misoprostol in induction of labor |
| title_sort | stripping of membranes versus vaginal misoprostol in induction of labor |
| topic | induction-delivery interval prolonged gestation stripping of membranes vaginal misoprostol |
| url | http://www.jmsr.eg.net/article.asp?issn=2537-091X;year=2019;volume=2;issue=2;spage=174;epage=179;aulast=Kamal |
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