Recent Advances in the Management Strategies for Buruli Ulcers

Buruli ulcer (BU) is a bacterial skin infection that is caused by <i>Mycobacterium ulcerans</i> and mainly affects people who reside in the rural areas of Africa and in suburban and beach resort communities in Australia. The infection typically begins as a painless papule or nodule that...

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Main Authors: Gabriela Loredana Popa, Alexandru Andrei Muntean, Mircea Ioan Popa
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/12/9/1088
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author Gabriela Loredana Popa
Alexandru Andrei Muntean
Mircea Ioan Popa
author_facet Gabriela Loredana Popa
Alexandru Andrei Muntean
Mircea Ioan Popa
author_sort Gabriela Loredana Popa
collection DOAJ
description Buruli ulcer (BU) is a bacterial skin infection that is caused by <i>Mycobacterium ulcerans</i> and mainly affects people who reside in the rural areas of Africa and in suburban and beach resort communities in Australia. The infection typically begins as a painless papule or nodule that gradually develops into a large ulcer that can cause substantial impairment, damaging soft tissues and even bones. Early detection and immediate treatment are crucial to preventing further tissue damage and any potential complications, although it is worth noting that access to proper therapeutic resources can be limited in certain areas. The most commonly used antibiotics for treating BU are rifampicin, streptomycin, and clarithromycin; efforts have recently been made to introduce new treatments that increase the effectiveness and adherence to therapy. This article presents the latest research and management strategies regarding BU, providing an updated and intriguing perspective on this topic.
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spelling doaj.art-a258def340cb4400aa65a91e033e0bfe2023-11-19T12:21:50ZengMDPI AGPathogens2076-08172023-08-01129108810.3390/pathogens12091088Recent Advances in the Management Strategies for Buruli UlcersGabriela Loredana Popa0Alexandru Andrei Muntean1Mircea Ioan Popa2Department of Microbiology, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Microbiology II, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Microbiology II, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaBuruli ulcer (BU) is a bacterial skin infection that is caused by <i>Mycobacterium ulcerans</i> and mainly affects people who reside in the rural areas of Africa and in suburban and beach resort communities in Australia. The infection typically begins as a painless papule or nodule that gradually develops into a large ulcer that can cause substantial impairment, damaging soft tissues and even bones. Early detection and immediate treatment are crucial to preventing further tissue damage and any potential complications, although it is worth noting that access to proper therapeutic resources can be limited in certain areas. The most commonly used antibiotics for treating BU are rifampicin, streptomycin, and clarithromycin; efforts have recently been made to introduce new treatments that increase the effectiveness and adherence to therapy. This article presents the latest research and management strategies regarding BU, providing an updated and intriguing perspective on this topic.https://www.mdpi.com/2076-0817/12/9/1088Buruli ulcer<i>Mycobacterium ulcerans</i>treatment
spellingShingle Gabriela Loredana Popa
Alexandru Andrei Muntean
Mircea Ioan Popa
Recent Advances in the Management Strategies for Buruli Ulcers
Pathogens
Buruli ulcer
<i>Mycobacterium ulcerans</i>
treatment
title Recent Advances in the Management Strategies for Buruli Ulcers
title_full Recent Advances in the Management Strategies for Buruli Ulcers
title_fullStr Recent Advances in the Management Strategies for Buruli Ulcers
title_full_unstemmed Recent Advances in the Management Strategies for Buruli Ulcers
title_short Recent Advances in the Management Strategies for Buruli Ulcers
title_sort recent advances in the management strategies for buruli ulcers
topic Buruli ulcer
<i>Mycobacterium ulcerans</i>
treatment
url https://www.mdpi.com/2076-0817/12/9/1088
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