A Rare Microsporidial Infection in Lamellar Corneal Tissue, following Transepithelial Photorefractive Keratectomy

The aim of this study was to report a unique case of microsporidial keratitis over deep anterior lamellar keratoplasty after transepithelial photorefractive keratectomy surgery that was successfully treated with therapeutic lamellar keratoplasty without recurrence at King Khaled Eye Specialist Hospi...

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Main Authors: Mohammad Alabduljabbar, Fatima Sirajuddin, Azza Maktabi, Rawan AlShabeeb
Format: Article
Language:English
Published: Karger Publishers 2023-04-01
Series:Case Reports in Ophthalmology
Subjects:
Online Access:https://www.karger.com/Article/FullText/528894
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author Mohammad Alabduljabbar
Fatima Sirajuddin
Azza Maktabi
Rawan AlShabeeb
author_facet Mohammad Alabduljabbar
Fatima Sirajuddin
Azza Maktabi
Rawan AlShabeeb
author_sort Mohammad Alabduljabbar
collection DOAJ
description The aim of this study was to report a unique case of microsporidial keratitis over deep anterior lamellar keratoplasty after transepithelial photorefractive keratectomy surgery that was successfully treated with therapeutic lamellar keratoplasty without recurrence at King Khaled Eye Specialist Hospital in Riyadh, Saudi Arabia. The patient presented with recurrent attacks of eye pain, redness, photophobia, and decreased vision. The patient was initially treated as a case of presumed herpetic keratouveitis using antiviral medication and topical steroids with partial improvement. During the last episode, the condition deteriorated and patient underwent therapeutic lamellar keratoplasty. Histopathology indicated an infected graft with evidence of microsporidial infection. The patient was discharged with complete corneal epithelial healing and no signs of recurrence during follow-up. Microsporidial infection is a rare cause of stromal keratitis that affects both immunocompetent and immunosuppressed patients. Microsporidia should be suspected after surface ablation refractive surgery if the patient presents with recurrent symptoms of keratoconjunctivitis or stromal keratitis that are partially responsive to topical steroid therapy.
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spelling doaj.art-a259fc95aadb4497a03e15b71ee1427d2023-05-12T12:24:18ZengKarger PublishersCase Reports in Ophthalmology1663-26992023-04-0114112713310.1159/000528894528894A Rare Microsporidial Infection in Lamellar Corneal Tissue, following Transepithelial Photorefractive KeratectomyMohammad Alabduljabbar0https://orcid.org/0000-0002-9016-2542Fatima Sirajuddin1Azza Maktabi2Rawan AlShabeeb3Anterior Segment Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi ArabiaCollege of Medicine, King Saud University, Riyadh, Saudi ArabiaPathology Department, King Khaled Eye Specialist Hospital, Riyadh, Saudi ArabiaAnterior Segment Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi ArabiaThe aim of this study was to report a unique case of microsporidial keratitis over deep anterior lamellar keratoplasty after transepithelial photorefractive keratectomy surgery that was successfully treated with therapeutic lamellar keratoplasty without recurrence at King Khaled Eye Specialist Hospital in Riyadh, Saudi Arabia. The patient presented with recurrent attacks of eye pain, redness, photophobia, and decreased vision. The patient was initially treated as a case of presumed herpetic keratouveitis using antiviral medication and topical steroids with partial improvement. During the last episode, the condition deteriorated and patient underwent therapeutic lamellar keratoplasty. Histopathology indicated an infected graft with evidence of microsporidial infection. The patient was discharged with complete corneal epithelial healing and no signs of recurrence during follow-up. Microsporidial infection is a rare cause of stromal keratitis that affects both immunocompetent and immunosuppressed patients. Microsporidia should be suspected after surface ablation refractive surgery if the patient presents with recurrent symptoms of keratoconjunctivitis or stromal keratitis that are partially responsive to topical steroid therapy.https://www.karger.com/Article/FullText/528894microsporidiastromal keratitiskeratoconjunctivitisdeep anterior lamellar keratoplasty
spellingShingle Mohammad Alabduljabbar
Fatima Sirajuddin
Azza Maktabi
Rawan AlShabeeb
A Rare Microsporidial Infection in Lamellar Corneal Tissue, following Transepithelial Photorefractive Keratectomy
Case Reports in Ophthalmology
microsporidia
stromal keratitis
keratoconjunctivitis
deep anterior lamellar keratoplasty
title A Rare Microsporidial Infection in Lamellar Corneal Tissue, following Transepithelial Photorefractive Keratectomy
title_full A Rare Microsporidial Infection in Lamellar Corneal Tissue, following Transepithelial Photorefractive Keratectomy
title_fullStr A Rare Microsporidial Infection in Lamellar Corneal Tissue, following Transepithelial Photorefractive Keratectomy
title_full_unstemmed A Rare Microsporidial Infection in Lamellar Corneal Tissue, following Transepithelial Photorefractive Keratectomy
title_short A Rare Microsporidial Infection in Lamellar Corneal Tissue, following Transepithelial Photorefractive Keratectomy
title_sort rare microsporidial infection in lamellar corneal tissue following transepithelial photorefractive keratectomy
topic microsporidia
stromal keratitis
keratoconjunctivitis
deep anterior lamellar keratoplasty
url https://www.karger.com/Article/FullText/528894
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