Construction of mouse liver aging model by hepatocyte organoid

Construction of mouse liver aging model by hepatocyte organoid

Objective Construction of mouse liver senescence model induced rapidly in vitro by 3D organoid culture. Methods Mouse hepatocytes were collected by two-step perfusion method and cultured in 3D. Organoids were preliminarily identified by morphology, qPCR and immunofluorescence. The function of hepato...

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Bibliographic Details
Main Author:	LU Yan, ZHOU Yabo, CHEN Jie
Format:	Article
Language:	zho
Published:	Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2023-04-01
Series:	Jichu yixue yu linchuang
Subjects:	primary hepatocyte\|organoid\|oleic acid\|reactive oxygen species\|aging
Online Access:	http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-4-554.pdf

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