Protein Kinase D3 (PKD3) Requires Hsp90 for Stability and Promotion of Prostate Cancer Cell Migration

Protein Kinase D3 (PKD3) Requires Hsp90 for Stability and Promotion of Prostate Cancer Cell Migration

Prostate cancer metastasis is a significant cause of mortality in men. PKD3 facilitates tumor growth and metastasis, however, its regulation is largely unclear. The Hsp90 chaperone stabilizes an array of signaling client proteins, thus is an enabler of the malignant phenotype. Here, using different...

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Bibliographic Details
Main Authors: Attila Varga, Minh Tu Nguyen, Kinga Pénzes, Bence Bátai, Pál Gyulavári, Bianka Gurbi, József Murányi, Péter Csermely, Miklós Csala, Tibor Vántus, Csaba Sőti
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cells
Subjects:
protein kinase D
heat shock protein 90
prostate cancer
migration
metastasis
Online Access:https://www.mdpi.com/2073-4409/12/2/212

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