Degradable tough chitosan dressing for skin wound recovery

The performance of wound dressing determines the effect of wound closure and recovery. Water absorption and bacteriostasis of wound dressings play an important role in wound recovery and healing. In this study, an optimized chitosan wound dressing-tough chitosan dressing (TCS) with high water absorp...

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Main Authors: Kong Yan, Tang Xiaoxuan, Zhao Yahong, Chen Xiaoli, Yao Ke, Zhang Liling, Han Qi, Zhang Luzhong, Ling Jue, Wang Yongjun, Yang Yumin
Format: Article
Language:English
Published: De Gruyter 2020-12-01
Series:Nanotechnology Reviews
Subjects:
Online Access:https://doi.org/10.1515/ntrev-2020-0105
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author Kong Yan
Tang Xiaoxuan
Zhao Yahong
Chen Xiaoli
Yao Ke
Zhang Liling
Han Qi
Zhang Luzhong
Ling Jue
Wang Yongjun
Yang Yumin
author_facet Kong Yan
Tang Xiaoxuan
Zhao Yahong
Chen Xiaoli
Yao Ke
Zhang Liling
Han Qi
Zhang Luzhong
Ling Jue
Wang Yongjun
Yang Yumin
author_sort Kong Yan
collection DOAJ
description The performance of wound dressing determines the effect of wound closure and recovery. Water absorption and bacteriostasis of wound dressings play an important role in wound recovery and healing. In this study, an optimized chitosan wound dressing-tough chitosan dressing (TCS) with high water absorption, high bacteriostasis, and degradability was developed. The chemical structure of chitosan remained stable during the process of optimized treatment, and an increase in mechanical properties was obtained for the dressing. After optimization, the water absorption and antibacterial properties of the chitosan dressing were greatly improved, which is significantly better than sodium alginate dressing. The authors believe that TCS dressing with high hygroscopicity and high bacteriostasis has great potential application value in the field of wound recovery and healing.
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spelling doaj.art-a25d29f61c40461f8f38af9ec90471562022-12-21T21:35:52ZengDe GruyterNanotechnology Reviews2191-90972020-12-01911576158510.1515/ntrev-2020-0105ntrev-2020-0105Degradable tough chitosan dressing for skin wound recoveryKong Yan0Tang Xiaoxuan1Zhao Yahong2Chen Xiaoli3Yao Ke4Zhang Liling5Han Qi6Zhang Luzhong7Ling Jue8Wang Yongjun9Yang Yumin10Key Laboratory of Eco-Textiles, Ministry of Education, College of Textile Science and Engineering, Jiangnan University, Wuxi, Jiangsu 214122, ChinaKey Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Nantong University, 226001, Nantong, ChinaKey Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Nantong University, 226001, Nantong, ChinaKey Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Nantong University, 226001, Nantong, ChinaKey Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Nantong University, 226001, Nantong, ChinaKey Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Nantong University, 226001, Nantong, ChinaKey Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Nantong University, 226001, Nantong, ChinaKey Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Nantong University, 226001, Nantong, ChinaKey Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Nantong University, 226001, Nantong, ChinaKey Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Nantong University, 226001, Nantong, ChinaKey Laboratory of Eco-Textiles, Ministry of Education, College of Textile Science and Engineering, Jiangnan University, Wuxi, Jiangsu 214122, ChinaThe performance of wound dressing determines the effect of wound closure and recovery. Water absorption and bacteriostasis of wound dressings play an important role in wound recovery and healing. In this study, an optimized chitosan wound dressing-tough chitosan dressing (TCS) with high water absorption, high bacteriostasis, and degradability was developed. The chemical structure of chitosan remained stable during the process of optimized treatment, and an increase in mechanical properties was obtained for the dressing. After optimization, the water absorption and antibacterial properties of the chitosan dressing were greatly improved, which is significantly better than sodium alginate dressing. The authors believe that TCS dressing with high hygroscopicity and high bacteriostasis has great potential application value in the field of wound recovery and healing.https://doi.org/10.1515/ntrev-2020-0105skin wound dressingchitosanhygroscopicitybacteriostasis
spellingShingle Kong Yan
Tang Xiaoxuan
Zhao Yahong
Chen Xiaoli
Yao Ke
Zhang Liling
Han Qi
Zhang Luzhong
Ling Jue
Wang Yongjun
Yang Yumin
Degradable tough chitosan dressing for skin wound recovery
Nanotechnology Reviews
skin wound dressing
chitosan
hygroscopicity
bacteriostasis
title Degradable tough chitosan dressing for skin wound recovery
title_full Degradable tough chitosan dressing for skin wound recovery
title_fullStr Degradable tough chitosan dressing for skin wound recovery
title_full_unstemmed Degradable tough chitosan dressing for skin wound recovery
title_short Degradable tough chitosan dressing for skin wound recovery
title_sort degradable tough chitosan dressing for skin wound recovery
topic skin wound dressing
chitosan
hygroscopicity
bacteriostasis
url https://doi.org/10.1515/ntrev-2020-0105
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AT zhaoyahong degradabletoughchitosandressingforskinwoundrecovery
AT chenxiaoli degradabletoughchitosandressingforskinwoundrecovery
AT yaoke degradabletoughchitosandressingforskinwoundrecovery
AT zhangliling degradabletoughchitosandressingforskinwoundrecovery
AT hanqi degradabletoughchitosandressingforskinwoundrecovery
AT zhangluzhong degradabletoughchitosandressingforskinwoundrecovery
AT lingjue degradabletoughchitosandressingforskinwoundrecovery
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